Nutritional disorder

This study tests two experimental drugs, PF-08653945 and PF-08653944, given alone or together, for weight loss in adults with overweight or obesity. About 872 participants will receive either the drugs or a placebo injection. The main goal is to see how much weight they lose over…

This Phase 3 trial tests a new medicine called MET097, given as a weekly injection, to help adults with overweight or obesity and type 2 diabetes lose weight. About 999 people will take part, with two-thirds getting the real drug and one-third getting a placebo. The study lasts a…

This study tests whether adding a continuous glucose monitor (CGM) and nutrition counseling to a food-as-medicine program helps adults with type 2 diabetes and food insecurity better manage their blood sugar. Sixty participants will be split into two groups: one gets the standard…

This study tests whether adding a nutrition education program for caregivers to standard oral iron therapy improves hemoglobin levels in children aged 1-5 with iron deficiency anemia. 150 children will be split into two groups: one gets iron pills alone, the other gets iron pills…

This study compares two ways of fortifying breast milk for preterm babies in the NICU. One group gets standard fortification, while the other gets a personalized mix based on real-time milk analysis. Researchers will track growth, brain scans, and development up to age 2 to see w…

This study tests whether adding a specially trained doula, along with home blood pressure and weight monitoring, can improve blood pressure in women who had high blood pressure during pregnancy. About 454 women will be randomly assigned to usual care or the doula program. The goa…

This study tests a new drug called CRB-913 for weight loss in people with obesity. It involves 252 participants and has two parts: first, measuring how the drug works in healthy adults, then comparing three doses against a placebo over 12 weeks. The goal is to check safety and ho…

This study tests a structured nutrition plan for 300 ICU patients who had abdominal surgery and cannot eat normally. The plan includes IV nutrition, oral supplements, and a device to measure calorie needs. Researchers will track infections, ICU stay length, and muscle loss to see…

This phase 2 trial tests different doses of tirzepatide in 414 adults with type 2 diabetes and obesity who already take metformin. The goal is to see if the drug helps with weight loss and blood sugar control. Participants receive either tirzepatide or a placebo for about 89 week…

This study planned to give a probiotic supplement or a placebo to toddlers aged 2–5 who were gaining weight faster than expected. The goal was to see if the probiotic could help manage weight gain over three months. However, the study was withdrawn before any children were enroll…

This study tests whether a small device that sends gentle electrical pulses to a nerve in the ear (the vagus nerve) can help people with obesity lose weight. About 131 adults with mild to moderate obesity will use the device daily for 6 months. Researchers will measure changes in…

This study is testing whether providing medically tailored meals along with nutrition counseling can improve the health and well-being of lung cancer patients who are economically disadvantaged or from minority groups. About 299 patients from four U.S. medical centers will receiv…

This study uses surveys to assess the hydration and nutrition habits and knowledge of frontline workers in PepsiCo manufacturing facilities. Researchers will measure understanding of hydration principles, actual drinking behaviors, and dietary patterns using validated questionnai…

Researchers are testing how well the body absorbs vitamin D, calcium, potassium, and magnesium from almond, soy, and oat milks compared with cow's milk. Healthy adults will avoid dairy and vitamin D-fortified foods for three weeks, then drink one type of milk daily for a week. Bl…

This study looks at how body composition, sleep, diet, and physical fitness are connected in ROTC cadets. Researchers will test body composition, collect surveys, and track activity to find lifestyle factors that boost performance. The goal is to improve screening methods and hel…

This study explores how body composition (normal weight obese vs normal weight lean) affects physical performance, sleep, and nutrition in female college cheerleaders and dancers. Researchers will measure jump height, muscle strength, energy levels, and sleep quality over 7 days.…

This study tests whether Eatable Alphabet cards—a fun, child-friendly nutrition tool—can help kids ages 2 to 10 with overweight or obesity eat more fruits and vegetables. About 160 children in a weight management program will use the cards, and parents will report changes in thei…

This study looks at how swallowing difficulties in people with multiple sclerosis (MS) relate to their nutrition and muscle function. Researchers will assess 34 ambulatory MS patients using questionnaires and physical tests. The goal is to better understand these connections to i…

This study looks at whether eating organic foods during pregnancy changes pesticide levels in the mother's urine and affects health markers like cholesterol. About 100 pregnant women will be randomly assigned to eat organic or conventional foods, following Norway's dietary guidel…

This study checks in on mothers and their children 20 years after a pregnancy diet trial. Back then, healthy pregnant women ate either a Mediterranean-style diet or their usual food. Now researchers measure heart health markers like cholesterol, waist size, and body fat to see if…

This study looks at whether weekly cooking classes can help adults eat better, waste less food, and feel less stressed. About 180 adults will attend in-person classes with cooking and tasting activities. Researchers will measure food waste and other changes over 10 weeks.

This study looks at how kangaroo care (holding your baby skin-to-skin) changes the nutrients and amount of breast milk in parents whose babies are in the NICU and can't breastfeed directly. About 25 parents will provide milk samples after holding their baby and after no contact, …

This study follows 200 premature babies who had a serious gut infection called necrotizing enterocolitis (NEC) to see how it affects their nutrition and growth by age 5. Researchers will check for problems like food allergies, poor growth, feeding difficulties, and other digestiv…

This study looks at a new slow-release protein product to find the smallest amount that keeps essential amino acids in the blood for 12 hours. About 21 healthy adults aged 18-40 will take part. The results will help decide the right dose for future studies on nutrition.

This study looks at how nutritional counseling and exercise affect telomeres—the protective caps on our chromosomes that shorten as we age—in elderly women. Researchers will compare women with and without obesity, measuring changes in telomere length and other aging markers after…

This study tests a 4-week group coaching program called FAVORes for caregivers of children in food-insecure households. The workshop teaches budgeting, nutrition, and how to find community resources. Researchers will survey 40 participants before and after the program to see if i…

About 11% of new mothers experience postpartum depression, which can affect their baby's growth and development. This study tests whether treating mothers with blue light therapy improves their infants' development and growth during the first year of life. Researchers will compar…

This study looks at how a personalized, calorie-restricted diet affects metabolism in overweight or obese Chinese adults. Researchers will measure how the body uses energy before and after a 12-week diet plan. The goal is to understand why people respond differently to the same d…

This study is surveying 2500 adults from Croatia, Greece, Italy, Slovenia, and Spain to explore how diet, exercise, sleep, stress, and social habits relate to physical and mental health. Participants complete an online questionnaire about their lifestyle and well-being. The goal …

This study looks at whether three easy-to-use health checklists (G8, CARG, and Frailty scales) can predict chemotherapy side effects in people aged 65 and older with solid tumors. Researchers will also check if these scores relate to nutrition blood tests and the need for a drug …