New weekly shot could help diabetics shed pounds
NCT ID NCT07400653
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 6 times
Summary
This Phase 3 trial tests a new medicine called MET097, given as a weekly injection, to help adults with overweight or obesity and type 2 diabetes lose weight. About 999 people will take part, with two-thirds getting the real drug and one-third getting a placebo. The study lasts about 21 months and will check how much weight participants lose and how their blood sugar changes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MET097 (a long-acting GLP-1 receptor agonist)
- What this could lead to
- If successful, this could provide a new weekly injection option for significant weight loss and better blood sugar control in people with type 2 diabetes.
- What could go wrong
- This is a Phase 3 trial, but results are not yet known. The drug may cause side effects, and not everyone may achieve meaningful weight loss. Placebo group limits certainty.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AMR Clinical
Fort Myers, Florida, 33912, United States
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Advanced Clinical Research
Miami, Florida, 33156, United States
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Alliance Research Institute
Canoga Park, California, 91304, United States
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Amarillo Medical Specialists LLP
Amarillo, Texas, 79124, United States
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Ashfields Primary Care Centre
Sandbach, CW11 1EQ, United Kingdom
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Bodyline Medical Clinic Warrington Civia Health
Paddington, WA1 3TZ, United Kingdom
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Bodyline Medical Clinic, Crosby Civia Health
Liverpool, L22 4QQ, United Kingdom
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Bodyline Medical Clinic, St Helens Civia Health
St Helens, WA9 1AF, United Kingdom
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Burke Primary Care
Morganton, North Carolina, 28655, United States
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CCR Ostrava
Ostrava, 702 00, Czechia
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CDG Studienambulanz Hartard
Munich, Bavaria, 80809, Germany
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CEDIC
Buenos Aires, C1060, Argentina
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CIDIM
Córdoba, X5000AVE, Argentina
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CIPADI - Centro Integral de Prevencion Y Atencion en Diabetes
Godoy Cruz, M5501ARP, Argentina
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Cardio D&R Košice
Košice, 040 22, Slovakia
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Cardiovascular Specialists of Willowbrook
Houston, Texas, 77070, United States
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Catalina Research Institute, LLC
Montclair, California, 91763, United States
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CenExcel Rocky Mountain Clinical Research, LLC
Englewood, Colorado, 80113, United States
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CenExel Anaheim Clinical Trials
Anaheim, California, 92801, United States
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CenExel CIT
Riverside, California, 92506, United States
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CenExel CNS - Collaborative Neuroscience Research
Los Alamitos, California, 90720, United States
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CenExel Denver CO (Rocky Mountain Clinical Research)
Englewood, Colorado, 80113, United States
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CenExel FCR - ForCare Clinical Research
Tampa, Florida, 33613, United States
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CenExel Salt Lake City UT (JBR Clinical Research)
Salt Lake City, Utah, 84107, United States
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CenExel iResearch, LLC
Decatur, Georgia, 30030, United States
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CenExel iResearch, LLC
Savannah, Georgia, 31405, United States
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Centricity Research Etobicoke Endocrinology
Etobicoke, Ontario, M9R 4E1, Canada
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Centricity Research Mirabel Multispecialty (Centricity Research)
Mirabel, Quebec, J7J 2K8, Canada
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Centro Medico Viamonte
Buenos Aires, Argentina
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Centro de Investigaciones Metabólicas (CINME)
Buenos Aires, C1056ABI, Argentina
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Centro de Investigaciones Médicas Tucuman
San Miguel de Tucumán, T4000AXL, Argentina
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Centru Medical "GRANDMED"
Oradea, 410032, Romania
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Centrul Medical Mediab - Mediab Srl
Târgu Mureş, 540142, Romania
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Centrum Badan Klinicznych PI-House Sp. z o.o.
Gdansk, 80-546, Poland
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Centrum Medyczne Pratia Gdynia
Gdynia, 81-338, Poland
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Centrum Medyczne Pratia Katowice
Katowice, 40-081, Poland
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Centrum Terapii Współczesnej J.M. Jasnorzewska Spółka Komandytowo-Akcyjna
Lodz, 90-338, Poland
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Centrum medyczne Pratia Bydgoszcz
Bydgoszcz, 85-796, Poland
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Civia Health Goodlettsville
Goodlettsville, Tennessee, 37072, United States
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Civia Health Nashville
La Vergne, Tennessee, 37086, United States
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Civia Health Sunderland
Hendon, CITY of Sunderland, SR1 1PB, United Kingdom
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Civia Health_Boots Birmingham
Birmingham, B4 7TA, United Kingdom
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Civia Health_Boots Nottingham
Nottingham, NG1 3QS,, United Kingdom
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Clifton Medical Centre
Rotherham, S651DA, United Kingdom
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Clinica Privada Velez Sarsfield
Córdoba, 5000, Argentina
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Core Healthcare Group
Cerritos, California, 90703, United States
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Cure Clinical Research
Orange, California, 92866, United States
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DIABEDA s.r.o.
Bratislava, 831 06, Slovakia
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Dallas Clinical Research Center (Pillar Clinical Research)
Richardson, Texas, 75080, United States
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Danes Camp Medical Centre
Northampton, NN4 0NY, United Kingdom
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DelRicht Research
Atlanta, Georgia, 30329, United States
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DelRicht Research
Springfield, Missouri, 65807, United States
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Diabetes Studienzentrum Wilhelmsburg
Hamburg, 21109, Germany
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Diabetespraxis Dr. Braun
Berlin, 13187, Germany
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Diabeteszentrum Hamburg-West
Hamburg, 22607, Germany
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Diacentrum Brandys n.L.
Brandys Nad Lebem, 25001, Czechia
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Diagnostic Consultative Center Aleksandrovska
Sofia, 1431, Bulgaria
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ERA Health Research
Redmond, Washington, 98052, United States
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ETG Siedlce
Siedlce, 08-110, Poland
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Ecg Médica S.L.
Valencia, 46015, Spain
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Edumed s.r.o.
Náchod, 54701, Czechia
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Ekamed Sp. z o. o.
Lublin, 20-718, Poland
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Etg Warszawa
Warsaw, 02-677, Poland
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Eximia EquiHealth Research
Durham, North Carolina, 27704, United States
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Eximia Research - NC, LLC
Raleigh, North Carolina, 27607, United States
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Fakultní nemocnice Královské Vinohrady
Prague, 100 34, Czechia
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Forum Austin (Civia Health)
Austin, Texas, 78578, United States
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Forum Health_Cary (Civia)
Cary, North Carolina, 27511, United States
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Fundatia Dr Victor Babes
Bucharest, 30303, Romania
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Future Medical Research (Civia Health)
Longwood, Florida, 32750, United States
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FutureMeds Berlin
Berlin, 10629, Germany
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FutureMeds Birmingham
Birmingham, B21 9RY, United Kingdom
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FutureMeds Frankfurt/Offenbach
Offenbach, 63065, Germany
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FutureMeds Glasgow McCafferty House
Glasgow, Scotland, G20 7BE, United Kingdom
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FutureMeds Liverpool
Bromborough, CH62 6EE, United Kingdom
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FutureMeds London
London, NW10 2PB, United Kingdom
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FutureMeds Newcastle
Newcastle upon Tyne, NE6 1SG, United Kingdom
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FutureMeds Olsztyn
Olsztyn, 10-165, Poland
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FutureMeds Plovdiv
Plovdiv, 4000, Bulgaria
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FutureMeds Teesside
Stockton-on-Tees, TS19 8PE, United Kingdom
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Futuremeds S.R.L., Brasov
Brasov, 500388, Romania
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Futuremeds S.R.L., Craiova
Craiova, 200115, Romania
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Futuremeds S.R.L., Galati
Galati, 800183, Romania
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Futuremeds Spain Cadiz
Chiclana de la Frontera, 11139, Spain
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Futuremeds Spain Madrid
Madrid, 28003, Spain
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Futuremeds Spain Sevilla
Seville, 41012, Spain
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GLRI El Paso Research
El Paso, Texas, 79936, United States
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Gemeinschaftspraxis Dres. H.Kittner und K.Hartig
Naunhof, 04683, Germany
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Hassman Research Institute
Marlton, New Jersey, 08053, United States
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Hightech Medical Services S.R.L (Centrul pentru Studiul Metabolismului)
Bucharest, 011053, Romania
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Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
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Hospital Universitario Virgen de la Victoria
Málaga, Málaga, 29010, Spain
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Hospital Virgen del Camino
Sanlúcar de Barrameda, 11540, Spain
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Hospital Vithas Sevilla
Castilleja de la Cuesta, 41950, Spain
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IRMED
Piotrkow Trybunalski, 97-300, Poland
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Indago Research & Health Center, Inc
Miami Lakes, Florida, 33016, United States
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Instituto Medico Catamarca (IMEC)
Santa Fe, S2000, Argentina
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Instituto de Investigaciones Clinicas Cordoba
Córdoba, X5000AAW, Argentina
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Institutul Clinic Fundeni
Bucharest, 022328, Romania
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Institutul National de Endocrinologie "C.I. Parhon"
Bucharest, 011863, Romania
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Instytut Diabetologii.sp.z.o.o.
Warsaw, 02-117, Poland
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JAL s.r.o.
Trnava, 91701, Slovakia
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Kiltearn Medical Centre
Nantwich, CW5 5NX, United Kingdom
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Klinische Forschung Berlin-Mitte GmbH
Berlin, 10117, Germany
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Klinische Forschung Dresden GmbH / Pratia
Dresden, 01069, Germany
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Klinische Forschung Hamburg GmbH / Pratia
Hamburg, 20253, Germany
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Klinische Forschung Karlsruhe GmbH
Karlsruhe, 76137, Germany
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LMC Diabetes & Endocrinology - Bayview (Centricity Research Toronto LMC Multispecialty)
Toronto, Ontario, M4G 3E8, Canada
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Lundquist Institute for Biomedical Innovation at Harbor- UCLA Medical Center
Torrance, California, 90502, United States
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MC Nevromedics Ltd.
Veliko Tarnovo, 5005, Bulgaria
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MHAT Botevgrad
Botevgrad, 2140, Bulgaria
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MHAT Sveta Karidad EAD
Plovdiv, 4004, Bulgaria
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Medical Center - Clinic Nova EOOD
Varna, 9020, Bulgaria
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Medical Center 4Life EOOD
Burgas, 8018, Bulgaria
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Medical Center Berbatov
Yambol, 8600, Bulgaria
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Medical Center Hera EOOD
Sofia, 1710, Bulgaria
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Medical Center New Polyclinic Gabrovo Ltd.
Gabrovo, 5300, Bulgaria
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Medical Center Zdrave 1
Kozloduy, 3320, Bulgaria
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Medical Centre Pratia Clinic EOOD
Varna, 9020, Bulgaria
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Medical group Kosice s.r.o.
Košice, 04001, Slovakia
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Medicome Sp. z o.o. Oświęcimskie Centrum Badań Klinicznych
Oświęcim, 32-600, Poland
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Medislim GmbH
Weinheim, 69469, Germany
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Medispektrum s.r.o.
Bratislava, 85101, Slovakia
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Medivasa s.r.o
Žilina, 010 01, Slovakia
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Medizentrum Essen Borbeck
Essen, 45355, Germany
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Metabolica Sp. z o.o., NZOZ METABOLICA Ośrodek Badań Klinicznych
Tarnów, 33-100, Poland
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Miami Eye Institute
Hollywood, Florida, 33024, United States
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Minimed S.R.L.
Bacau, 600274, Romania
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Multiprofile Hospital for Active Treatment Dobrich AD (MHAT Dobrich AD)
Dobrich, 9300, Bulgaria
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Murray Vision Center PC
Salt Lake City, Utah, 84107, United States
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NZOZ Centrum Medyczne KERmed
Bydgoszcz, 85-231, Poland
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Nemocnice Jihlava
Jihlava, 58601, Czechia
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Neuro-Sight Vision Care
Lakewood, Colorado, 80226, United States
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Nuevas Tecnologías en Diabetes y Endocrinología S.L.
Seville, 41003, Spain
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Optimal Research Sites, LLC
Orange City, Florida, 32763, United States
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Oviedo Medical Research
Oviedo, Florida, 32765, United States
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Pantheon Clinical Research
Bountiful, Utah, 84010, United States
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Panthera Biopartners Limited - Enfield
Enfield, EN3 4GS, United Kingdom
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Panthera Biopartners Limited - Glasgow
Glasgow, G51 4RY, United Kingdom
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Panthera Biopartners Limited - Preston
Preston, PR2 9QB, United Kingdom
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Panthera Biopartners Limited - Rochdale
Rochdale, OL11 4AU, United Kingdom
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Panthera Biopartners Limited - Sheffield
Sheffield, S2 5FX, United Kingdom
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Panthera Biopartners Limited - York
York, YO24 4LJ, United Kingdom
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Patient First Clinical Trials (PFCTRIALS)
Lutherville, Maryland, 21093, United States
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Pedro P. Ylisastigui, MD
Fort Myers, Florida, 33912, United States
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Poliklinika Váš Lekár
Bratislava - Ružinov, 91109, Slovakia
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Practice Dr. Kirsch and Colleague, Zentrum fur klinische Forschung
Cologne, 51069, Germany
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Praktyka Lekarska Ewa Krzyzagorska
Poznan, 61-655, Poland
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Pratia Chojnice
Chojnice, 89-600, Poland
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Pratia Pardubice
Pardubice, 53002, Czechia
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Praxis Reinfeld Mitte
Holstein, 23858, Germany
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Praxis am Markt - Dr. Bernd Becker
Essen, 45355, Germany
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Prevencia - 2000 - Medical Center for Prehospital Medical Care OOD
Stara Zagora, 6000, Bulgaria
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Primary clinical Research
Papillion, Nebraska, 68046, United States
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Private Practice Adjacent to For Eyes Optical
Hialeah, Florida, 33014, United States
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Quality Clinical Research Inc
Omaha, Nebraska, 68114, United States
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ResTrial s.r.o.
Prague, 18100, Czechia
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Research Centers of America
Hollywood, Florida, 33024, United States
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Sahana Optometry PLLC dba Family Eye Wellness
Holly Springs, North Carolina, 27540, United States
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Santa Familia PTG Lodz
Lodz, WOJ Lodzkie, 90-302, Poland
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Sc Gensan Srl/Policlinica Astra
Sibiu, 550371, Romania
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Southmead Hospital
Bristol, BS10 5NB, United Kingdom
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Studienzentrum FMZ Radowsky
Leipzig, Saxony, 04179, Germany
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Synexus Glasgow Clinical Research Centre
Bellshill, ML4 3NJ, United Kingdom
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Synexus Manchester Clinical Research Centre
Manchester, M15 6SE, United Kingdom
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Synexus Midlands Clinical Research Centre
Birmingham, B15 2SQ, United Kingdom
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Synexus Polska Sp z o.o.
Gdansk, 80-382, Poland
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Synexus Polska Sp. Z O.O. Oddzial W Katowicach
Katowice, 40-040, Poland
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Synexus Polska Sp. z o.o. Oddzial w Gdyni
Gdynia, 81-537, Poland
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Synexus Polska Sp. z o.o., Oddzial w Czestochowie
Częstochowa, 42-202, Poland
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Synexus Polska Sp. z o.o., Oddzial w Lodzi
Lodz, 90-127, Poland
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Synexus Polska Sp. z o.o., Oddzial w Warszawie
Warsaw, 02-672, Poland
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Synexus Polska Sp. z o.o., Oddział w Poznaniu
Poznan, 60-702, Poland
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Synexus Polska Sp. z o.o., Oddział we Wrocławiu
Wroclaw, 50-381, Poland
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Synexus/Trialmed Prague
Prague, 120 00, Czechia
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Tatratrial s.r.o.
Rožňava, 048 01, Slovakia
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The Wharton Medical Clinic Clinical Trials Inc
Hamilton, Ontario, L8L 5G8, Canada
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Trialmed CRS
Piotrkow Trybunalski, 97-300, Poland
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Tribe Clinical Research LLC. - Spartanburg
Spartanburg, South Carolina, 29301, United States
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Tribe Clinical Research LLC.- Greenville
Greenville, South Carolina, 29607, United States
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Velocity Clinical Research Germany
Berlin, 10787, Germany
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Zdrowie Osteo Medic sc L i A Racewicz, A i J Supronik
Bialystok, 15-351, Poland
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Zentrum für klinische Forschung Allgäu-Oberschwaben
Wangen, 88239, Germany
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