Myopia

This study compares two types of special glasses (DIMS and DOT) to control nearsightedness in children aged 6 to 12 who also have intermittent exotropia (a type of eye misalignment). Researchers want to see which lens works better and whether the glasses affect eye coordination. …

This study tests two types of daily disposable contact lenses designed to slow the progression of myopia (nearsightedness) in children aged 7 to 12. Over two years, 126 Hong Kong Chinese children will wear either a special lens or a standard single-vision lens, with their eyes me…

This study tests two types of modified spectacle lenses designed to slow the progression of myopia (nearsightedness) in children aged 6 to 13. Over one year, researchers will measure changes in the back of the eye (choroid), eye length, and prescription strength. The goal is to s…

This study tests whether special research glasses can reduce the difference in prescription between the two eyes in children aged 6 to 13 with myopic anisometropia (when one eye is much more nearsighted than the other). Twenty children will wear the study glasses and have their e…

This study tests two new types of multifocal glasses designed to manage myopia (nearsightedness) in children aged 8 to 15. Twenty kids who already wear myopia-control glasses will try each new design for a short time to see how well they see and how comfortable they feel. The goa…

This study will enroll about 3,890 children aged 8-12 who still have rapidly worsening nearsightedness (myopia) even after using orthokeratology (Ortho-K) lenses. Researchers will compare four approaches: continuing Ortho-K alone, adding low-dose atropine eye drops, using lenses …

This study tests special glasses called D.D.C dual-control lenses to see if they can slow down worsening nearsightedness (myopia) in children aged 6 to 14. Over 24 months, 316 kids will wear either the new lenses or standard glasses. The goal is to measure changes in eye prescrip…

This study tests whether special spectacle lenses can slow the progression of myopia (nearsightedness) in European children aged 6 to 12. A total of 180 kids will wear one of three lens designs for two years. The main goal is to measure changes in eye length and prescription stre…

This study tests whether oral dietary supplements can improve the health of the back of the eye in children with nearsightedness (myopia). About 156 children aged 8-13 will take either a supplement or a placebo for a period, and researchers will measure changes in the thickness a…

This study tests if low-intensity red light therapy can slow or stop the worsening of high and extreme myopia (severe nearsightedness) in adults aged 18 to 45. The treatment has shown promise in children, but its effects in adults are unknown. The goal is to prevent vision loss a…

This trial tests a red light device that uses LED light to control myopia (nearsightedness) in children aged 6 to 18. About 206 kids will use either the real device or a fake one to see if the red light can slow eye growth and reduce the need for stronger glasses. The study focus…

This study tests whether low-dose atropine eye drops (0.05%) can slow down worsening nearsightedness in children aged 1 to 7 who have had cataract surgery with an artificial lens implant. Fifty children will receive the drops for 12 months, and researchers will measure changes in…

This study tests if using a special LED red light device twice a day, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be randomly assigned to different groups to find the best treatmen…

This study tests whether repeated low-intensity red light can treat myopia (nearsightedness) in adults aged 18 to 35. Thirty participants will use a red light device 1 to 3 times daily. Researchers will measure changes in eye length and prescription strength to see if the treatme…

This trial tests whether an enhanced monofocal intraocular lens, set for monovision (one eye for distance, one for near), improves vision without glasses in people with both cataracts and high myopia. Sixty-six participants will receive the lens in both eyes and be followed for o…

This study tests whether low-dose atropine eye drops (0.05%) can slow the progression of myopia (nearsightedness) in children. Forty-five kids with worsening myopia will receive one drop of atropine in one eye and a placebo drop in the other eye every night for 24 months. The mai…

This study will test a new, non-invasive eye scanner called wide field OCTA in 200 people with various eye diseases, including age-related macular degeneration, diabetic retinopathy, and dry eye. The goal is to see if this device can provide better images of blood vessels in the …

This study tests a new device designed to measure nearsightedness and astigmatism. Researchers will compare its accuracy to standard tools used by eye doctors. Thirty adults aged 18-39 who wear glasses will participate. The goal is to see if the new device works as well as curren…

This study checks if a Turkish version of the DDIVAT digital vision test gives the same results as the standard Snellen eye chart. About 200 Turkish-speaking adults, with or without glasses, will take both tests. No drugs or procedures are involved, and there are no risks.

This study will test a new artificial intelligence (AI) system that reads eye scans (OCT) to diagnose common blinding eye diseases like diabetic retinopathy, glaucoma, and age-related macular degeneration. Researchers will collect 2000 eye scans from patients at Peking Union Medi…

This study tests whether dual focus contact lenses can prevent myopia (nearsightedness) in children aged 8 to 10 who are at risk. Over 2 years, researchers will check if these lenses stop the onset of myopia compared to standard lenses. If it works, it could offer a simple way to…

This study tests whether special glasses lenses can prevent nearsightedness (myopia) in children aged 6 to 8 who are not yet nearsighted. About 255 children will wear either a new type of lens or a standard lens for at least 8 hours a day for one year. Researchers will check thei…

This study tests whether pressing tiny pellets on ear points can delay or prevent nearsightedness (myopia) in children aged 4 to 14 who are at high risk. It compares ear acupressure, low-dose atropine eye drops, and a combination of both. The goal is to find a safe, non-drug way …

This study tests whether low-dose atropine eye drops can prevent nearsightedness (myopia) in children aged 6 to 9 who are at risk. Over 12 months, children receive daily drops, with the dose adjusted based on how fast their eyes change. The goal is to find the best dose to keep t…

This study tests a 24-week school program to prevent myopia, obesity, and mental health problems in children aged 8-11. The program includes animated videos, family activities, and health lessons. Researchers will compare these kids to those receiving standard health education, t…

This study tests whether sending regular health education messages about eye care to parents via WeChat can improve how children use their eyes and slow or prevent nearsightedness. About 1,330 third-grade students in China will take part, with their guardians receiving the messag…

This study tests whether replacing some regular gym classes with specialized physical education courses can prevent common health issues like nearsightedness, overweight, anxiety, and depression in junior high students. Two hundred students will be randomly assigned to either the…

This study tests two different methods of centering laser eye surgery (SMILE) in people with nearsightedness and a large angle kappa—a natural offset between the visual axis and pupil center. One method uses a 50% correction, the other 100%. Researchers want to see which approach…

This trial tests whether a small adjustment during SMILE laser surgery—compensating for the eye's natural offset (kappa angle)—can improve visual quality for people with nearsightedness. About 224 participants will receive either standard SMILE or SMILE with this compensation. Re…

This study tests a special laser to help people who had cataract surgery with a standard lens implant see better up close or correct remaining blurry vision. About 12 participants will receive the laser treatment, and doctors will check if it safely improves near or distance visi…

This study tests a new excimer laser for LASIK surgery to correct mild nearsightedness (up to -1.00 diopter) with or without astigmatism. About 32 adults aged 22 and older will receive the treatment in one or both eyes. The goal is to see if the laser safely and accurately improv…

This study tests a new daily disposable contact lens called ST-1 against an existing lens, Miru 1day UpSide, in 63 people with nearsightedness. Participants will wear the lenses daily for 3 months and have their vision and eye comfort checked regularly. The goal is to see if the …

This early-stage trial tests a non-invasive device that uses controlled UV light to reshape the cornea, potentially reducing the need for reading glasses in people with presbyopia. The study will enroll 25 adults aged 40 to 65 with healthy corneas. The main goal is to see if the …

This study will use a special imaging device (AS-OCT) to measure the thickness of the cornea's outer layer in 360 adults with nearsightedness, farsightedness, astigmatism, or normal vision. The goal is to see if different vision problems have unique thickness patterns. Participan…

This study looks at whether giving eye doctors AI-generated measurements from retinal images helps them write more accurate and complete reports. About 29 ophthalmologists and trainees will be randomly assigned to use AI tools or just the original images. A panel of senior expert…

This study will measure how eye pressure changes after common laser vision correction surgeries like PRK, LASIK, and femtosecond laser. Researchers will compare two measurement methods—Corvis CT and the standard applanation tonometer—in 50 people aged 19 to 35 with mild to modera…

This study will measure how pupil size and eye shape affect visual quality in 300 people with normal eyes or after refractive surgery. Researchers will use questionnaires and special instruments to track symptoms and eye measurements. The goal is to better understand what influen…

This study will compare 40 nearsighted children to 40 children with normal vision, all aged 8 to 13. Researchers will measure how much oxygen the retina uses and look at blood flow and eye structure. The goal is to learn whether low oxygen plays a role in causing myopia. No treat…

This study follows 100 children ages 4 to 8 who currently have perfect vision to see who develops nearsightedness (myopia) over 2 to 5 years. Researchers will track eye measurements and daily habits to uncover why some children become nearsighted while others don't. The goal is t…

This study looks at how the length of the eye and the amount of nearsightedness or farsightedness relate to the health of the optic nerve and surrounding layers. Researchers will use a special camera (OCT) to take detailed images of the eye in 266 adults. The goal is to better un…

This study will analyze corneal tissue that is normally thrown away during a common myopia surgery called CLEAR (or SMILE). Researchers will test the tissue's strength and structure to learn more about how the cornea behaves. The goal is to improve future eye surgeries by underst…