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Could a medicated contact lens ease pain after laser eye surgery?

NCT ID NCT07705763

Symptom relief Sponsor: Madina Teaching Hospital Faisalabad Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This trial compares pain relief from bandage contact lenses soaked in the anti-inflammatory drug ketorolac versus plain lenses after photorefractive keratectomy (PRK), a type of laser eye surgery. PRK often causes significant pain in the first few days as the cornea heals. The study will measure pain levels at several time points and track how quickly the eye's surface recovers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ketorolac tromethamine 0.5%-soaked bandage contact lenses
What this could lead to
If effective, this approach could offer a simple, sustained way to control pain after PRK without repeated eye drops.
What could go wrong
This is a small, early-stage study with 60 participants, so results may not apply broadly. There is a risk of side effects from ketorolac, such as delayed healing or allergic reaction.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants selected to undergo photorefractive keratectomy for correction of refractive error after complete workup. * Participants willing to participate in the study after detailed explanation of the research purpose. Exclusion Criteria: * Known hypersensitivity to NSAIDs or ketorolac. * Presence of any systemic diseases affecting wound healing.

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Conditions

The condition(s) this trial relates to.

refractive error

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Photorefractive keratectomy Refraction error

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Madina Teaching Hospital Faisalabad

    Faisalābad, Punjab Province, 38000, Pakistan

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