Lower respiratory tract disorder
MONDO:0000270A disease involving the lower respiratory tract.
Also known as: disease of lower respiratory tract, disease or disorder of lower respiratory tract, disorder of lower respiratory tract, lower respiratory tract disease, lower respiratory tract disease or disorder
7952 clinical trials for this condition and its sub-types, 18 tagged with Lower respiratory tract disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Lower respiratory tract disorder
-
Lung disorder 251 trials · 7,091 incl. sub-types
33 sub-types
- Lung neoplasm 1,371 trials · 4,046 incl. sub-types Sub-types →
- Obstructive lung disease 36 trials · 1,074 incl. sub-types Sub-types →
- Respiratory failure 280 trials · 790 incl. sub-types Sub-types →
- Interstitial lung disease 257 trials · 729 incl. sub-types Sub-types →
- Pneumonitis 15 trials · 646 incl. sub-types Sub-types →
- Bronchiolitis 51 trials · 104 incl. sub-types Sub-types →
- Acute lung injury 90 trials
- Fungal lung infectious disease 6 trials · 57 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Aspiration pneumonia 33 trials
- Acute chest syndrome 30 trials
- Middle lobe syndrome 29 trials
- Pulmonary systemic sclerosis 27 trials
- Pulmonary coin lesion 24 trials
- Pulmonary alveolar proteinosis 9 trials · 13 incl. sub-types Sub-types →
- Pulmonary artery disease 12 trials
- Rheumatoid arthritis-associated interstitial lung disease 12 trials
- Occupational lung disease 4 trials · 8 incl. sub-types Sub-types →
- Restrictive pulmonary disease 8 trials
- Neonatal aspiration syndrome 1 trial · 6 incl. sub-types Sub-types →
- Lung abscess 3 trials
- Pneumonic plague 3 trials
- Hantavirus pulmonary syndrome 2 trials
- Pulmonary immaturity 2 trials
- Wilson-Mikity syndrome 0 trials
- Dystrophic pulmonary ossification 0 trials
- Pulmonary alveolar microlithiasis 0 trials
- Pulmonary embolism and infarction 0 trials
- Pulmonary plasma cell granuloma 0 trials
- Pulmonary venoocclusive disease 0 trials Sub-types →
- Shrinking lung syndrome 0 trials
- Silo filler disease 0 trials
- Vanishing lung syndrome 0 trials
-
Tracheal disorder 6 trials · 1,091 incl. sub-types
8 sub-types
- Chronic obstructive pulmonary disease 937 trials · 1,054 incl. sub-types Sub-types →
- Tracheal stenosis 20 trials
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
- Congenital tracheomalacia 6 trials
- Trachea neoplasm 2 trials · 5 incl. sub-types Sub-types →
- Isolated tracheo-esophageal fistula 2 trials
- Laryngotracheoesophageal cleft 1 trial Sub-types →
- Tracheal calcification 0 trials
-
Bronchial disorder 19 trials · 1,012 incl. sub-types
6 sub-types
- Asthma 725 trials · 820 incl. sub-types Sub-types →
- Bronchiectasis 119 trials · 120 incl. sub-types Sub-types →
- Bronchitis 24 trials · 50 incl. sub-types Sub-types →
- Bronchial neoplasm 20 trials · 38 incl. sub-types Sub-types →
- Non-syndromic bridging bronchus 0 trials
- Non-syndromic congenital bronchial atresia 0 trials
-
Pleural disorder 15 trials · 177 incl. sub-types
5 sub-types
- Pleural neoplasm 5 trials · 97 incl. sub-types Sub-types →
- Pneumothorax 35 trials · 45 incl. sub-types Sub-types →
- Pleural empyema 20 trials Sub-types →
- Pleurisy 2 trials · 9 incl. sub-types Sub-types →
- Congenital chylothorax 0 trials
-
Tracheobronchitis 5 trials · 55 incl. sub-types
2 sub-types
- Bronchitis 24 trials · 50 incl. sub-types Sub-types →
- Tracheitis 2 trials · 7 incl. sub-types Sub-types →
Most studied deeper sub-types
-
Sound waves vs. superbugs: can a simple ultrasound curb unnecessary antibiotics in kids?
Disease control Recruiting nowThis study investigates whether using lung ultrasound (a safe, radiation-free imaging technique) can help doctors decide when to stop antibiotics in children and teens hospitalized with lower respiratory tract infections like pneumonia. Half of the participants will receive a lun…
Sponsor: American University of Beirut Medical Center • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
-
New hope for immunocompromised patients with severe parainfluenza
Disease control Recruiting nowThis study tests an experimental drug called DAS181 in people with weakened immune systems who have a serious lung infection caused by parainfluenza virus. The goal is to see if the drug helps them breathe without extra oxygen and reduces the risk of death. About 274 participants…
Phase 3 • Sponsor: Ansun Biopharma, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
-
New blood test aims to slash unnecessary antibiotics in ER lung infections
Disease control Recruiting nowThis study tests a new blood test called MeMed BV in about 1,300 adults with suspected lower respiratory infections (like bronchitis or pneumonia) in the ER. The goal is to see if the test helps doctors prescribe antibiotics only when truly needed, reducing unnecessary use. Parti…
Sponsor: MeMed Diagnostics Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
-
New pill aims to stop recurring chest infections in adults
Prevention Recruiting nowThis study tests whether Buccalin tablets can reduce the number of lower respiratory tract infections in adults who get them often. 240 participants will receive either Buccalin or a placebo for 12 months. The goal is to see if the treatment lowers infection episodes compared to …
Phase 4 • Sponsor: Laboratorio Farmaceutico SIT srl • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
-
Smart alerts aim to curb antibiotic overuse in Kids' lung infections
Knowledge-focused Recruiting nowThis study tests whether computer-based decision support tools can help doctors reduce unnecessary antibiotic use in children with lower respiratory tract infections like pneumonia, bronchiolitis, and asthma flare-ups. Most of these infections are caused by viruses, not bacteria,…
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
-
1,000+ kids tracked from birth to unlock secrets of childhood lung infections
Knowledge-focused Recruiting nowThis study follows 1,088 newborns in Colombia and Panama until age 5 to learn how often respiratory infections happen, which viruses or bacteria cause them, and why some children get sicker than others. Families report symptoms twice a week and provide nasal and blood samples dur…
Sponsor: Eduardo Lopez -Medina • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC