Female infertility

This trial tests whether a daily dietary supplement called WeNatal For Her can improve markers of female fertility in women who are trying to conceive. Forty women aged 18-45 will take three capsules each morning for three menstrual cycles. Researchers will measure blood levels o…

This study looked at 99 IVF patients with endometriosis (a condition where uterine-like tissue grows elsewhere) and a positive BCL6 test. It compared a cheap oral pill (norethindrone acetate) to an expensive injection (Depo Lupron) given before embryo transfer. The goal was to se…

This study tested whether Erzhi Tiangui granules, a traditional Chinese herbal blend, could improve live birth rates in women aged 35 to 43 with poor ovarian response undergoing IVF. The trial involved 480 participants across multiple centers and compared the herbal granules to a…

This completed Phase 3 trial compared two fertility drugs—follitropin delta (Rekovelle) and follitropin alfa (Gonal-F)—in 301 Chinese women undergoing IVF. The goal was to see which starting dose leads to the best number of eggs retrieved. Participants received daily injections f…

This study looked at whether adding vaginal estradiol or oral guaifenesin to standard fertility treatment (clomiphene citrate) could improve pregnancy rates. 90 women with infertility were randomly assigned to one of three groups. The goal was to see if these add-ons helped with …

This study tested whether two natural supplements (acetyl L-carnitine and myo/chiro-inositol) can help women with PCOS ovulate and become pregnant. 120 women aged 18-35 with PCOS-related infertility took part. The goal was to see if these supplements improve ovulation and pregnan…

This study tested whether postbiotic suppositories (containing natural bacteria byproducts) could improve the vaginal microbiome in 15 infertile women aged 30-45 who had at least two failed IVF attempts. Participants used one suppository daily for 8 weeks. Researchers measured ch…

This phase 3 trial tested whether an oral tablet called SHR7280 works as well as the standard injection (ganirelix) for preventing early ovulation in women undergoing IVF. The study involved 317 infertile women aged 20-39. If effective, the pill could offer a more convenient opti…

This study compared two imaging methods for diagnosing female infertility: MRI with a contrast dye and traditional X-ray. The goal was to see if MRI, which uses no radiation, could provide a complete and accurate assessment. Forty women participated, and researchers measured how …

Researchers are testing whether adding alpha-lipoic acid, an antioxidant supplement, to standard letrozole treatment helps infertile women with polycystic ovary syndrome ovulate and become pregnant. The trial enrolls 150 women aged 18 to 35 who are trying to conceive. Both groups…

This study tested whether a simple mindfulness exercise—noticing natural changes in mood and body throughout the day—could improve wellbeing for couples dealing with infertility. 70 patients and their partners took part. The goal was to see if this low-cost, easy-to-learn approac…

This study tested whether flushing follicles with a special needle during egg retrieval helps women who produce few eggs in IVF. 257 women with fewer than 5 mature follicles were randomly assigned to standard aspiration or aspiration plus flushing. The goal was to see if flushing…

This study tested whether a special supplement containing antioxidants and probiotics could improve egg quality in women with polycystic ovary syndrome (PCOS) undergoing IVF. Twenty women took either the supplement or a placebo (just folic acid) during their IVF cycle. Researcher…

Researchers at the University of California, San Francisco are running a long-term study to see whether children conceived through infertility treatment have different metabolic profiles than other children. The study has two parts: one looks back at children already born, and th…

This pilot study tests a streamlined ovarian stimulation protocol for women undergoing fertility treatment. Participants receive a single injection of corifollitropin alfa plus daily oral clomiphene citrate, instead of the usual multiple daily injections. Researchers will measure…

This study looks at how sleep length and quality may affect the success of in vitro fertilization (IVF) in women. Participants will wear a ring-shaped device that tracks sleep patterns before and after a frozen embryo transfer. The goal is to see if sleep parameters like total sl…

This study looked at 112 people with known differences in their sex chromosomes (X and Y) to better understand how these variations affect health, especially infertility. Participants underwent physical exams, blood and urine tests, imaging, and sensory checks over about 5 days. …

This study looked at whether using frozen embryos instead of fresh ones in IVF leads to more live births. 237 women took part, and researchers compared pregnancy rates and baby health. The goal was to see if freezing embryos helps the womb lining work better.

This early-stage study tested the safety and tolerability of a new drug called HS-10518 in 60 healthy premenopausal women in China. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moved through the body. The goal was…

This study looked at whether the level of thyroid-stimulating hormone (TSH) in the blood affects the success of a fertility treatment called ICSI. Researchers measured TSH in 180 women on day 2-3 of their menstrual cycle and then tracked egg retrieval, fertilization, and pregnanc…

This study looked at over 1,800 frozen embryo transfer cycles to see if a woman's body mass index (BMI) affects whether the transfer can be done as planned and if it leads to pregnancy. Researchers compared obese and non-obese women using different hormone preparation methods. Th…

This study looked at how different doses and methods of giving progesterone (vaginal, under the skin, or muscle injection) affect the structure and function of the uterine lining in women preparing for embryo transfer. 109 healthy women with regular cycles took part, and research…

This study looked at whether using a special freezing medium designed just for eggs, versus a universal medium for all stages, affects pregnancy rates in egg donation. Researchers analyzed data from 111 donor cycles. The goal is to see if the type of freezing medium makes a diffe…

This study looked at 255 women who chose to have permanent sterilization (tubal ligation) surgery. Researchers compared three different surgical approaches to see which one led to the best recovery and highest patient satisfaction. The goal was to help doctors and patients choose…

This study looked at whether flushing the uterus with a low dose of the hormone hCG right after egg retrieval could improve pregnancy rates in women undergoing IVF. Researchers measured immune markers and blood flow in the uterus to see if the flush made the womb more receptive t…