Could a vaginal postbiotic boost IVF success?
NCT ID NCT07278024
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether postbiotic suppositories (containing natural bacteria byproducts) could improve the vaginal microbiome in 15 infertile women aged 30-45 who had at least two failed IVF attempts. Participants used one suppository daily for 8 weeks. Researchers measured changes in vaginal bacteria and pregnancy rates in a subsequent IVF cycle. The study is small and has no control group, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- postbiotic bacteriocin suppositories
- What this could lead to
- If it works, this could point toward a simple way to improve pregnancy chances in women with repeated IVF failures.
- What could go wrong
- This is a very small, early study with only 15 people and no comparison group. Results may not apply to others, and the treatment might not improve pregnancy rates.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Kaohsiung City, Taiwan
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