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Do infertility treatments leave a metabolic mark on children?

NCT ID NCT03799107

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers at the University of California, San Francisco are running a long-term study to see whether children conceived through infertility treatment have different metabolic profiles than other children. The study has two parts: one looks back at children already born, and the other follows families from early pregnancy onward. About 2,020 children will take part. Researchers will measure blood markers such as glucose, insulin, cholesterol, and liver enzymes to understand any long-term effects of infertility and its treatments.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If the study finds a link between infertility treatment and children's metabolism, it could guide monitoring and care for families who use these treatments.
What could go wrong
This is an observational study, so it can show patterns but not prove cause and effect. Findings may reflect other factors such as parental health or lifestyle, and results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

2,020 people

The number who actually took part.

Started

Jul 2017

Finished

Jun 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Retrospective: \- children conceived by parent(s) who sought evaluation/treatment for infertility Prospective: \- people seeking evaluation/treatment for infertility

Ages

4 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Retrospective arm Inclusion criteria: \- children conceived by parent(s) who sought evaluation/treatment for infertility Exclusion criteria: \- Children with chronic medical illnesses that prevent a study visit Prospective arm Inclusion criteria: \- seeking evaluation/treatment for infertility Exclusion criteria: \- none

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Conditions

The condition(s) this trial relates to.

female infertility infertility disorder male infertility

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infertility Infertility primary Infertility secondary Infertility unexplained Infertility, female Infertility, male

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94115, United States

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