Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could your genes predict when fertility fades?

NCT ID NCT00501800

Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers at the University of California, San Francisco, are studying how genes and environment affect the rate at which women's ovaries age. They will measure antral follicle counts by ultrasound and collect DNA from 1,080 women aged 25 to 45 with regular menstrual cycles. The goal is to find markers that predict when fertility declines and menopause begins, which could improve family planning and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If researchers identify genetic markers of ovarian aging, doctors could one day predict when a woman's fertility will decline and tailor family planning advice.
What could go wrong
This observational study cannot prove cause and effect, and its findings may not apply to women outside the five ethnic groups studied. It may take years to yield useful predictions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,080 people

The number who actually took part.

Started

Nov 2006

Finished

Jul 2012

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Study Population will be drawn from members of Northern California Kaiser Permanente Health Plan utilizing the Kaiser Permanente Division of Research database to identify potentially eligible subjects.

Ages

25 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 25-45 years * Self-identifying as one of five specified race/ethnicities - Caucasian, Chinese, Filipino, African-American, or Hispanic (Mexican or Central American). * Regular menstrual cycles (monthly bleeding with an interval of 25-35 days) * Uterus and ovaries required. Exclusion Criteria: * Chronic medical illness such as heart, kidney, or liver disease or diabetes * Endometriosis of ovary * Prior surgical procedure for removal of ovarian cyst(s) * Epilepsy * Lupus * Invasive cancer excluding squamous or basal cell skin cancers * Prior treatment with chemotherapy or radiation therapy * Use of any oral/systemic estrogen or progestin containing medication within a 3-month period * Use of any central nervous system active medications known to disrupt the menstrual cycle (e.g. clonidine, aldomet) * Psychiatric history involving functionally debilitating disturbance such as psychosis or major mood disorder requiring hospitalization or change in occupational or social functioning. * Currently pregnant or breastfeeding * Unable to speak and read English, Cantonese, or Spanish * Concurrent participation in a clinical drug trial.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Infertility are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infertility

Contacts and locations

Locations

  • University of California San Francisco

    San Francisco, California, 94143, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.