Communication disorder

This study tests a computer-based practice method to help people with aphasia—a language disorder often caused by stroke—retrieve words more easily. Participants practice naming pictures with or without cues and receive feedback, repeating items until they meet a learning goal. T…

This study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…

This early study tests a small, wireless brain implant designed to help people with severe speech problems communicate by thought. Four adults with conditions like locked-in syndrome or ALS will get the implant and learn to control it. The main goal is to see if the device is saf…

This study tests a short case management program for people who have been involuntarily admitted to a psychiatric hospital. The program, designed with input from people who have experienced coercion, provides up to five sessions with a nurse or social worker starting during the h…

This study looks at whether a program called EMPOWER, led by trained peer supporters, can help homeless veterans with substance use or mental health issues stay engaged in care and avoid repeated hospital stays or emergency visits. About 278 veterans in permanent supportive housi…

This study is testing a new cognitive assessment called the ExéSem battery, designed to help doctors tell the difference between language problems caused by memory loss versus those caused by thinking difficulties. Researchers will enroll 140 people, including those with Alzheime…

This study will test a machine-assisted system that uses five simple behavioral tasks—like responding to their name or pointing—to screen toddlers for autism. Researchers will enroll 1,000 children aged 1.5 to 2.5 years, including those with autism, developmental delays, language…

This study tests whether low-intensity focused ultrasound (LIFU), a gentle sound wave technique, can safely improve speech fluency in people who stutter. Twenty adults who stutter will receive LIFU or a sham treatment, and researchers will measure changes in stuttering severity a…

This study looks at whether posture and tongue position affect how children pronounce Hebrew sounds. Researchers will test if adding muscle-strengthening exercises to regular speech therapy helps kids learn correct pronunciation faster. About 80 children with and without speech i…

This study tests whether an AI-based app called HiDongDong can improve speech in children aged 2 to 14 who have trouble pronouncing words. Forty-eight children will either use the app at home for 20 minutes a day, five days a week, or receive standard speech therapy. The goal is …

This study tests whether a type of cognitive training called Action-Based Cognitive Remediation (ABCR) can improve thinking skills in people with various psychiatric conditions like depression, schizophrenia, anxiety, PTSD, and autism. Participants will complete computer exercise…

This study explores whether a non-invasive brain stimulation technique called tDCS can be practically used during routine speech therapy for people who have had a stroke and now have aphasia (trouble speaking or understanding language). Researchers will enroll 30 stroke survivors…

This trial tests whether an intensive, personalized speech therapy program (ICAP) helps people with post-stroke aphasia communicate better and feel better. 334 adults who had a stroke at least 3 months ago will be randomly assigned to either ICAP (100 hours over 4 weeks) or stand…

This study compares two treatments to help 150 children aged 8-11 with developmental language disorder learn passive sentence structures. One treatment uses repetition and listening, while the other teaches grammar rules directly. Children will be tested before, right after, and …

This study tests whether a mild electrical current applied to the scalp (tDCS) can improve naming ability in people who have trouble speaking after a recent stroke. Twenty-eight adults with aphasia will receive either real or sham stimulation over five days. The goal is to see if…

This study aims to see if online speech therapy works as well as face-to-face sessions for children aged 5 to 11 with repaired cleft palate. Sixty-four children will receive 30-minute speech therapy twice a week for 10 weeks, either online or in person. Researchers will measure i…

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can help people over 70 recover swallowing after a stroke. Twenty participants will receive either active or sham stimulation alongside standard speech therapy for three weeks. Researchers wi…

This study tests whether a special type of speech training using five musical tones can help people with aphasia (trouble speaking) after a stroke. Researchers will enroll 120 adults who had a stroke and have non-fluent aphasia. Participants will receive either five-tone therapy …

This study compares voice therapy delivered in-person versus via telehealth for adults aged 55 and older with age-related voice problems. Thirty participants will receive four sessions of PhoRTE® voice exercises either face-to-face or through video calls. Researchers will measure…

This study tests a special light therapy (850 nm) on 66 adults who had a stroke within the past year and now have trouble speaking or understanding language (aphasia). The goal is to see if shining this light on the head can improve brain activity and language skills. Participant…

This Phase 2 pilot study will test whether a single high dose of psilocybin (the active ingredient in magic mushrooms) combined with speech therapy can improve fluency and reduce struggle in 25 adults who stutter. Researchers will measure changes in stuttering severity and brain …

This study tests whether listening to music for 30 minutes a day for 8 weeks can improve attention, language, and quality of life in people with aphasia after a stroke. Researchers will compare music listening to audiobook listening and a control group. The trial involves 45 adul…

This study interviews bereaved parents and oncologists to understand how they discussed uncertainty during a child's cancer treatment. The goal is to find better ways for doctors and families to communicate about what the future may hold. Participants include parents whose child …

This study tests a new program called CapExchange, where people with stable mental health conditions exchange practical skills with others in their community. The goal is to see if this approach is practical and helpful for improving well-being and social connection. About 10 to …

This study aims to adapt and validate a French version of the Recovery Assessment Scale (RAS), a questionnaire that measures how people feel about their own recovery from mental health conditions. Researchers will ask 260 adult psychiatric patients in France to fill out the RAS a…

This study tests whether adding a career counseling program called Purposeful Pathways to standard job training helps veterans with mental health and substance use disorders find and keep quality jobs. About 254 veterans from three VA sites will take part. The goal is to improve …

This study looks at how often people develop speech or swallowing problems after a jaw-advancement surgery for obstructive sleep apnea. Researchers will measure nasality, speech, and swallowing in 28 adults before and after surgery at five different times. The goal is to better u…

This study will test a tool called the Health Improvement Profile (HIP) in a mental health inpatient unit. The HIP is a checklist that helps clinicians spot physical health problems like high blood pressure or poor diet in people being treated for mental illness. Researchers will…

This study will follow 120 Mandarin-speaking children with autism and typically developing children to understand how speech develops over time. Researchers will use parent reports and play sessions to track language skills. The goal is to create models that help predict speech p…

This study looks at how the brain uses feedback to control speech in 90 adults aged 18-50, including people who stutter, have dyslexia, and those with typical speech. Participants will do speech tasks, have an MRI scan, and receive mild brain stimulation to see how different brai…

This study watches real conversations between healthcare staff and people with dementia after hip fracture surgery. The goal is to find which words and phrases work best to encourage patients to stand or walk early. Researchers will record up to 50 care sessions on hospital wards…

This study looks at whether using simulation (practicing with mannequins or actors) helps first-year nursing students become better communicators compared to traditional teaching methods like role-play and group discussion. Fifty students will be randomly assigned to either simul…

This study aims to better understand psychiatric disorders, thinking problems, and treatment side effects in 2000 cancer patients and their close relatives. Researchers will compare those with and without mental health issues to find patterns and improve care. No new treatments a…

This study will compare how well an AI program (Blings) measures speech clarity in 40 adults with speech disorders from stroke or other neurological conditions. Two speech therapists will also rate the same speech samples. The goal is to see if the AI can reliably replace or assi…

This study will check how much psychiatric clients know about occupational therapy (OT) and whether their expectations are realistic. It will also evaluate how well OT interns explain health information and conduct interviews. Researchers will develop new tools to measure these s…

This study tests a program to help people with certain genetic mutations share their results with at-risk relatives and make informed decisions about genetic testing and care. About 2100 adults in the U.S. who speak English or Spanish will take part. The program provides free gen…

This study will test whether using a metaverse environment with virtual patients helps nursing students improve their communication skills, stay engaged in learning, and reduce daydreaming. One hundred fourth-year nursing students will be randomly assigned to either metaverse tra…

This study tests a training program where pediatricians practice talking about contraception with computer-generated avatars of a teen and her mother. The goal is to see if this boosts doctors' confidence and skills in shared decision-making. The study will enroll 166 medical res…