Magic mushroom compound could help people who stutter

NCT ID NCT07296328

First seen Jan 04, 2026 · Last updated Jun 23, 2026 · Updated 33 times

Summary

This early-stage study will test whether a single high dose of psilocybin (the active ingredient in magic mushrooms) combined with speech therapy can improve fluency and reduce struggle in 25 adults who stutter. Researchers will measure changes in stuttering severity and brain activity. The goal is to see if this approach is safe and worth studying further.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    New York, New York, 10016, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

psilocybin

What this could lead to

If it works, this could point toward a new treatment approach for stuttering that combines a psychedelic drug with speech therapy.

What could go wrong

This is a very small, early-stage pilot study with only 25 people and no placebo group. The results may not apply to everyone who stutters, and psilocybin can cause intense psychological effects.

Conditions

The condition(s) this trial relates to.

stutter disorder Stuttering

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.