Cholelithiasis

This study looked at whether a drug called Remaxol can help people with gallstones and a serious complication called obstructive jaundice. Obstructive jaundice happens when a gallstone blocks the bile duct, causing yellowing of the skin and eyes. The study involved 286 adults who…

This study tested a technique where a balloon is used to widen the bile duct opening and clear stones during emergency gallbladder removal surgery. 100 adults with bile duct stones took part. After surgery, an MRI scan checked if all stones were gone. The goal was to see if this …

This study looked at 400 people with liver cirrhosis who had large or complex bile duct stones that couldn't be removed during a first procedure. Doctors placed either one or two plastic stents to help drain the bile and make stones easier to remove later. The goal was to find th…

This study looked at whether placing a temporary plastic tube (stent) in the bile duct after removing gallstones helps prevent stones from returning while patients wait for gallbladder surgery. 200 adults with both gallbladder and bile duct stones took part. Half got the stent, h…

This study tested a new way to open the bile duct during an ERCP procedure. Instead of the standard pull-type cut, doctors used a special hooked knife (ASD) designed to cut only the circular muscle layer, potentially causing less damage. Over 1,500 patients were randomly assigned…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of infection after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if the drug reduces surgical site infections compared to a …

This study tested two types of endoscopes used in ERCP, a procedure to treat bile duct and pancreas problems. One scope had a single-use plastic cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how often complications …

This study tested whether adding acupuncture to standard anti-nausea drugs could better prevent nausea and vomiting after laparoscopic gallbladder removal. 270 adults scheduled for surgery received either acupuncture plus standard drugs or standard drugs alone. The goal was to se…

This study looked at whether giving more IV fluids (aggressive hydration) during an ERCP procedure can prevent pancreatitis, a common complication. 126 adults having their first ERCP were randomly assigned to receive either standard or extra fluids. The goal was to see if extra f…

This study tested a new way to remove a stubborn gallbladder during keyhole surgery. When the gallbladder is too large or thick to pull out easily, surgeons often make a bigger cut, which can cause bleeding and pain. The new method uses three tiny star-shaped cuts around the open…

This study tested whether a nerve block called a TAP block can reduce pain after laparoscopic gallbladder removal. Sixty adults were split into two groups: one received the block plus standard painkillers, the other only standard painkillers. Researchers measured pain levels and …

This study tested whether a rectointercostal nerve block can reduce pain and the need for strong painkillers after laparoscopic gallbladder removal. 60 adults having elective surgery received the block as part of their pain management plan. The goal was to see if it lowers opioid…

This study tested a 12-week online mind-body program for adults with chronic conditions like heart failure, cancer, and liver disease. The program included mindful movement, meditation, breathwork, and coping skills. Researchers measured changes in anxiety, depression, fatigue, a…

This completed study tested a new painkiller called tegileridine in 150 adults who had gallbladder surgery. Participants received either the drug or a placebo through a vein, along with standard pain management. The goal was to see if tegileridine reduces pain and the need for ex…

This study looked at whether reducing noise during the start of anesthesia (when you go to sleep) can improve recovery after laparoscopic gallbladder removal. 105 adults having planned surgery were included. Researchers measured pain, nausea, vomiting, heart rate, blood pressure,…

This study looked at whether a TAP block (a type of nerve block) can reduce pain after laparoscopic gallbladder removal. Sixty adults were split into two groups: one got the TAP block with numbing medicine after surgery, the other did not. Researchers measured pain levels and how…

This study looked at whether adding dexmedetomidine to a common numbing medicine (bupivacaine) could improve pain control after laparoscopic gallbladder removal. Thirty adults having elective surgery were randomly assigned to receive either the combo or bupivacaine alone, sprayed…

This study tested whether aromatherapy foot massage can reduce pain, improve sleep, and speed recovery after laparoscopic gallbladder removal. 103 adults received two 10-minute foot massages with essential oils after surgery. Researchers measured pain, sleep quality, and recovery…

This study tested two common painkillers, ketamine and lidocaine, to see which works better for pain after gallbladder removal. 76 adults were randomly assigned to receive one of the drugs right after surgery. Researchers measured their pain levels over the next 24 hours. The goa…

This study tested two common drugs, lidocaine and magnesium sulfate, to see which one works better for pain after gallbladder removal surgery. 168 adults received one of the two drugs during surgery, and their pain levels were checked at several points over 24 hours. The goal was…

This study tested different ways to control pain after laparoscopic gallbladder removal in 160 adults. Patients received either a TAP block (an injection into the abdominal wall muscles), local anesthetic at the incision sites, both, or no extra pain relief. The TAP block group r…

This study tested whether a TENS device (which sends mild electrical pulses through the skin) can help people recover after laparoscopic gallbladder removal. 140 adults were randomly assigned to receive TENS or standard care in the first 24 hours after surgery. Researchers measur…

This study tested two types of nerve blocks—Quadratus Lumborum (QL) and Erector Spinae (ESP)—to see which provides better pain relief after abdominal surgery. 100 adults having surgery for colorectal, prostate, or kidney cancer, or gallbladder removal, received one of the blocks …

This study compared two methods of creating the first opening (pneumoperitoneum) in laparoscopic gallbladder removal: one through the belly button and one just below it. Researchers looked at how fast each method was, complications, pain, hospital stay, and cosmetic satisfaction.…

This study looked at 13 people aged 15 to 70 who had their gallbladder and bile duct stones removed. Right after surgery, doctors placed a small tube in the bile duct to measure pressure, then checked it weekly for six weeks. The goal was to understand how the bile duct heals and…

This study looked at 1435 patients with acute cholangitis (a bile duct infection) who had an ERCP procedure. Researchers analyzed bile samples to understand which bacteria were causing the infections and how resistant they were to antibiotics. The goal was to find patterns that c…

This study looked at whether using a special ultrasound probe (IDUS) during a procedure to remove bile duct stones can help predict if stones will come back. 248 adults at high risk for recurrence were randomly assigned to get IDUS or not. Researchers tracked stone return, need f…

This study looked at 130 patients with gallstones who had their gallbladder removed by keyhole surgery. Researchers compared the ultrasound results done before surgery with what the surgeon actually found during the operation. The goal was to see if ultrasound can predict when th…

This study looked at 237 patients who had a single surgery to remove both their gallbladder and any gallstones stuck in the bile duct. Researchers wanted to see if the COVID-19 pandemic changed how safe or effective this procedure was. They found that the surgery remained a good …

This study looked back at the medical records of 609 people treated for gallbladder inflammation (cholecystitis) in Villavicencio, Colombia, between 2019 and 2022. The goal was to understand how quickly patients received care, what treatments they got, and how many had complicati…

This study looked at 360 patients who had gallstone removal surgery with a T-tube drain. Doctors compared a new continuous stitching method to the traditional interrupted stitch for closing the bile duct. The goal was to see which method is faster and just as safe. Results could …

This study looked at 150 adults having gallbladder surgery to see if fatty liver disease (MAFLD) makes a special imaging technique less clear. The imaging uses a dye to help surgeons see bile ducts. Researchers found that fatty liver can reduce image quality and created a way to …

This completed study followed over 1,000 people who had an ERCP procedure to see if having chronic gallbladder disease increases the chance of complications like infection or inflammation. Researchers tracked issues such as post-ERCP cholecystitis, pancreatitis, and cholangitis. …

This study looked at 75 patients in Nepal who had bile duct stones removed using a reused Ambu aScope, a cheap disposable scope normally used for breathing tubes. The goal was to see if reusing it is safe and effective in low-resource settings where expensive scopes aren't availa…

This study looked at 128 people having gallbladder surgery to see if giving them extra oxygen before anesthesia (instead of using a mask to help them breathe) would reduce stomach bloating and sore throat. The researchers compared two groups: one that got mask ventilation and one…

This study tested whether using a dye called indocyanine green along with infrared light helps surgeons see the bile ducts more clearly during gallbladder removal surgery. Over 600 adults having their gallbladder taken out were randomly assigned to either standard white light or …

This study looked at over 121,000 procedures to remove gallstones from the bile duct using a scope (ERCP). Researchers wanted to see if the level of sedation given during the procedure affected whether stones were left behind. They found that deeper sedation might help the doctor…