New opioid aims to ease pain after abdominal surgery
NCT ID NCT07277153
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study tested a new painkiller called tegileridine in 150 adults who had gallbladder surgery. Participants received either the drug or a placebo through a vein, along with standard pain management. The goal was to see if tegileridine reduces pain and the need for extra opioids in the first 48 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tegileridine (a painkiller given through a vein)
- What this could lead to
- If it works, this could provide a new option for managing pain after abdominal surgery, possibly reducing the need for other opioids.
- What could go wrong
- This is a completed phase 4 trial, so results are available. However, tegileridine is a narcotic and may cause side effects like nausea, vomiting, or breathing problems. Its benefit over existing painkillers is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Anesthesiology,the Second Affiliated Hospital of Hainan Medical University
Haikou, China