Cholelithiasis

This study looks at 100 people with gallstones that have moved into the bile duct. One group gets the usual two-step treatment: first a scope to remove the bile duct stone, then surgery to remove the gallbladder. The other group gets a single surgery where the gallbladder is remo…

This study compares a new robotic-assisted endoscope to the standard method for removing gallstones stuck in the common bile duct. The robot aims to protect doctors from radiation and repetitive strain injuries while keeping the procedure just as effective. About 200 adults with …

This study looks at whether measuring certain substances in bile and blood can more accurately diagnose cancer in people with bile duct blockages. Researchers will compare these new tests with standard methods in 500 adults undergoing a procedure called ERCP. The goal is to find …

This study tests whether removing the fallopian tubes during planned gallbladder removal surgery is safe for women aged 45 and older. The goal is to see if this extra step can help prevent ovarian cancer without causing more complications. About 300 women will take part, with hal…

This study looks at two ways to give a pain-relieving injection (TAP block) to people having their gallbladder removed by keyhole surgery. One group gets the injection only on the right side, the other gets it on both sides. Researchers will track how long it takes before patient…

This study looks at whether teaching patients about gallstones and gallbladder removal surgery before the operation can improve their quality of life afterward. About 200 adults having gallbladder surgery will either get standard hospital care or extra educational sessions. Resea…

This study tests whether adding the anti-nausea drug ondansetron to a standard saline wash during gallbladder surgery can better control pain and nausea afterward. Forty adults having their gallbladder removed will be randomly assigned to receive either a plain saline wash or one…

This study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…

This study follows 650 children and adults with LPAC syndrome, a rare condition that causes repeated gallstones even after gallbladder removal. Researchers will collect medical history, lab results, and imaging data over 5 years to describe the disease's full range of symptoms an…

This study is a registry that collects information from patients who have a procedure called percutaneous cholangiopancreatoscopy (PCPS). During PCPS, doctors use a tiny camera to see inside the bile ducts and remove stones or take tissue samples. The goal is to learn how well th…

This observational study plans to enroll 120,000 people with various chronic diseases like pancreatitis, diabetes, and arthritis. Researchers will collect blood samples and health data to study how genetics and lifestyle affect disease progression. The goal is to find common dise…