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Which ventilation mode breathes better during laparoscopic surgery?

NCT ID NCT07709039

Knowledge-focused Sponsor: Mehreen Mirza Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This trial compares two ways of delivering mechanical ventilation—volume-controlled and pressure-controlled—in adults undergoing laparoscopic gallbladder removal under general anesthesia. The goal is to see which mode better maintains lung flexibility and removes carbon dioxide during surgery. Sixty patients aged 25 to 50 with mild or no health issues are randomly assigned to one of the two ventilation methods.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If one ventilation method proves better, it could guide anesthesia practices to improve breathing support during laparoscopic surgeries.
What could go wrong
This is a small, early-stage study focused on short-term breathing measures, not long-term outcomes. Results may not apply to all patients or surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jan 2026

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 25-50 years. * Either sex. * ASA physical status I or II. * Scheduled for elective laparoscopic cholecystectomy under general anaesthesia. * Written informed consent obtained. Exclusion Criteria: * ASA physical status III or IV. * Body mass index (BMI) greater than 35 kg/m². * Significant pulmonary disease (e.g., COPD, asthma, restrictive lung disease). * Significant cardiovascular disease. * Pregnancy. * Previous upper abdominal surgery. * Conversion to open cholecystectomy. * Refusal to participate.

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Conditions

The condition(s) this trial relates to.

cholelithiasis Pneumoperitoneum

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cholelithiases General anaesthesia Laparoscopic cholecystectomy

Contacts and locations

Locations

  • Nishtar Medical University and Hospital, Multan

    Multan, Punjab Province, 00000, Pakistan

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