University Of Wisconsin, Madison

This study tests a new way of using targeted drugs (panitumumab or cetuximab) to better control metastatic colorectal cancer that cannot be removed by surgery. About 34 people with left-sided tumors will receive these drugs early in their treatment, with the goal of keeping the d…

This study tests a clinic-supported mobile health program called Connections for up to 806 HIV patients who also have substance use disorders. Participants get support from their care team and peer mentors for one year to help them stay virally suppressed and attend appointments.…

This study aimed to see if a living donor liver transplant, given after standard chemotherapy, could help people with colon cancer that spread to the liver and could not be removed by surgery. It planned to enroll 25 donor-recipient pairs (50 people total) and follow recipients f…

This study tests a special lollipop that collects saliva to check for strep throat in children ages 5 to 17. The goal is to see if the lollipop works as well as the standard throat swab. If successful, it could make testing more comfortable for kids.

This study tests whether an 8-session nutrition education program is practical and well-liked by patients in a general medicine clinic. The program focuses on eating more fiber-rich foods like fruits, vegetables, and whole grains. About 42 adults with prediabetes, diabetes, or ob…

This study tests a program called RESTORE that helps nursing staff redesign their work to reduce job demands and increase resources. About 470 nurses who provide direct patient care will participate. Researchers will measure burnout using surveys and interviews to see if the prog…

This study planned to test whether taking lorazepam, a medicine for anxiety, before getting an IUD could help reduce pain and worry during the procedure. It was designed for 25 adults at a family medicine clinic. However, the study was withdrawn before any participants were enrol…

This study looks at whether a 10-week supervised physical activity program is practical and helpful for mothers of children with developmental disabilities. About 30 mothers will take part, with some starting the program right away and others joining later. The goal is to see if …

This study looks at whether an 8-week mindfulness program, done remotely via an app, can improve mental health and recovery in people who had ACL knee surgery. About 47 participants aged 16-40 will be randomly assigned to mindfulness or standard care. The goal is to reduce anxiet…

This study looks at whether a mindfulness program designed for pregnancy and parenting can lower anxiety in expectant mothers. Researchers will enroll 60 pregnant women with elevated worry and randomly assign them to either the mindfulness class or a standard childbirth education…

This early-phase study tested whether ketamine-assisted psychotherapy is safe and doable for adolescents aged 15-17 with severe PTSD. Five teens were to receive three ketamine doses along with therapy sessions over six weeks. The study is currently suspended, so results are not y…

This early-stage study looks at whether psilocybin, the active ingredient in magic mushrooms, is safe and practical to use alongside behavioral support for people with methamphetamine use disorder. Twelve adults with the condition will receive two oral doses and be monitored for …

This study looks at whether a program called I-SITE can help more people with diabetes get their eyes checked using telemedicine (remote eye photos). It involves over 12,000 patients in urban health systems. The goal is to see if this approach increases screening rates for diabet…

This study was designed to find out how temperature, visuals, and sounds together affect a person's comfort and body signals like heart rate and skin temperature. Healthy adults aged 18-40 would have watched short videos in two different climate-controlled rooms and reported how …

This study looks at how Salvation Army staff can help people who smoke learn about and use free services to quit. About 233 adults who use Salvation Army services will take part. Researchers will track how many people are referred to the Wisconsin Tobacco Quit Line and how many a…

This study compares two methods for training surgeons to use a communication framework called Better Conversations, which helps patients understand surgery goals, risks, and what to expect. About 60 surgeons and 660 patients will take part. The goal is to see if automated trainin…

This study looks at whether getting one-on-one help from a navigator makes it more likely that people on Medicaid will renew their coverage. Over 119,000 Wisconsin residents who need to renew their fee-for-service Medicaid are included. Researchers will compare different types of…

This study looks at whether special scans and genetic tests can help predict how well high-risk prostate cancer responds to radiation and hormone therapy. About 30 participants will be followed for up to 5 years. The goal is to find early signs of poor response, not to test a new…

This study looks at vitamin A levels in 90 adults with vocal fold leukoplakia, a condition that causes white patches on the vocal cords. Researchers will measure vitamin A in the liver and blood and compare it to the type of lesion. The goal is to better understand the role of vi…

This study looks at whether a protein called AXL in head and neck tumors affects how well a combination of two drugs (imatinib and cetuximab) works. About 15 adults with head and neck cancer will receive these drugs in the short window between diagnosis and their standard treatme…

This study looks at a training program designed to improve how surgeons talk with patients and colleagues. About 600 surgeons and surgical trainees will take part to see if the training helps them feel more confident and skilled in communication. The goal is to find out if this p…

This study looks at how a special clinic helps older adults get ready for major abdominal surgery. Researchers will watch and talk to doctors, staff, and patients to understand what works well and what could be better. The goal is to create a clear plan that other hospitals can u…

This study tests a new type of MRI that measures brain tissue health in people with multiple sclerosis (MS). The goal is to see if these scans can predict problems with thinking and memory. Researchers will enroll 75 adults with MS and compare their brain scans to cognitive test …

This study looks at different methods to help patients keep their dental appointments in clinics that serve mostly low-income and uninsured people. The researchers will compare reminder messages, motivational communication, and walk-in visits to see which works best. About 48 cli…

This study tests a communication tool called Best Case/Worst Case-ICU for older adults (50+) with serious injuries in the ICU. Researchers want to see if it improves how families and doctors talk, reduces stress for clinicians, and shortens ICU stays. About 4,500 patients, 1,500 …