University Of Wisconsin, Madison

This early-stage trial tested a combination of an experimental fusion protein (hu14.18-IL2), radiation, and two immunotherapy drugs (nivolumab and ipilimumab) in people with advanced melanoma that couldn't be surgically removed. The goal was to find the safest dose and check for …

This study tested a special type of radiation (pulse reduced dose rate) combined with the drug bevacizumab in 49 people with recurrent high-grade gliomas (brain tumors). The goal was to see if this combination could help patients live longer. Participants received radiation over …

This study aimed to measure how targeted muscle reinnervation (TMR) surgery affects quality of life and function in people who have had a major limb amputation. TMR was done either at the time of amputation or later. Only 2 people took part before the study was stopped early, so …

This study looked at whether two doses of psilocybin, given with behavioral support, are safe and practical for people with methamphetamine use disorder. Only 5 people enrolled before the study ended early. The goal was to check for serious side effects and see if participants co…

This study aimed to see if a mental health app could help head and neck cancer survivors with depression. Participants were asked to use the app for 6 weeks and fill out surveys. The study was stopped early and only enrolled 1 person, so no meaningful results were obtained.

This study tested a program called 5Minutes4Myself, designed to help caregivers of autistic children (ages 8-21) manage stress and improve their well-being. Participants worked with a coach to create a personalized wellness plan and used a phone app with reminders and mindfulness…

This study tested whether using a special image-guidance system (AxiEM Stealth) helps doctors place a brain drain more accurately at the bedside compared to the usual freehand method. The drain is needed to relieve pressure in the brain. The study included 31 adults who needed th…