Can stem cells cure radiation dry mouth? tiny study hopes to find out
NCT ID NCT04489732
First seen Apr 11, 2026 · Last updated Jun 23, 2026 · Updated 8 times
Summary
This early-stage pilot study tests whether injecting a patient's own stem cells into a saliva gland can safely relieve dry mouth caused by radiation therapy for head and neck cancer. Six survivors who finished cancer treatment at least two years ago will receive a single injection. The main goal is to check for side effects, not yet to prove the treatment works.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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University of Wisconsin
Madison, Wisconsin, 53705, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mesenchymal stromal cells (stem cells from the patient's own bone marrow)
What this could lead to
If it works, this could point toward a new way to relieve chronic dry mouth in cancer survivors.
What could go wrong
This is a very early, tiny pilot study with only 6 people. It mainly checks safety, not effectiveness, and may not lead to a proven treatment.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.