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Gulf war Veterans' brain blood flow under the microscope

NCT ID NCT04586049

Knowledge-focused Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how brain blood flow and nerve signals work in veterans who served in the Gulf War (1990-1992) and have Gulf War Illness. Researchers will compare them to healthy veterans using breathing tests, ultrasound, and MRI scans. The goal is to learn more about why some veterans experience cognitive decline, but no treatment or cure is being tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 70 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects for this study will include Veterans with Gulf War Illness and Veterans without Gulf War Illness. Both men and women are eligible to participate in this study.

Ages

45 to 68 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Deployed to the Persian Gulf between 1990-1992 * Body mass \<300 lbs * Diagnosis of Gulf War Illness based on CMI/CDC and Kansas definitions or No diagnosis of Gulf War Illness Exclusion Criteria: * Current or lifetime evidence of: Type II diabetes, neurological disease, cancer treatment, rheumatoid arthritis, lupus, bipolar disorder, psychotic disorders, or mood disorders with psychotic features * Current illicit substance use or partial remission for less than 1 year * Taking multiple sedatives or anticonvulsant medications * Currently pregnant * Absolute contraindications to exercise testing * Contraindications to MRI * Other significant medical conditions at investigator's discretion

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Conditions

The condition(s) this trial relates to.

persian gulf syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain blood flow Neurovascular control

Contacts and locations

Locations

  • University of Wisconsin-Madison

    Madison, Wisconsin, 53706, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.