University Of Arizona

This study tests whether a time-efficient breathing exercise program can help lower blood pressure in adults aged 50 and older who have moderate to severe sleep apnea but cannot use standard CPAP therapy. Researchers will measure blood pressure changes over 36 weeks. The goal is …

This study tests whether a combination of two creams—calcipotriene (a form of vitamin D) and 5-fluorouracil (a chemotherapy agent)—can prevent skin cancer in organ transplant recipients. These patients have a high risk of developing skin cancer due to their long-term use of immun…

This study tests a nutrition program designed specifically for African patients with type 2 diabetes. 64 adults in Benin will either receive the tailored program or standard care. The goal is to see if the program helps lower blood sugar and improve eating habits over 6 months, w…

This study tests a combination of two medicines (atomoxetine and oxybutynin) given at bedtime for 6 months to children with Down syndrome who have obstructive sleep apnea. The goal is to see if the treatment improves sleep breathing problems and thinking skills. The study involve…

This study tests whether six weeks of special breathing exercises (called inspiratory muscle strength training) can improve heart and lung function in people with pulmonary hypertension, a condition where high blood pressure strains the heart and lungs. Four adults already schedu…

This study tests a combination of two drugs, atezolizumab and cabozantinib, in 30 people with advanced pancreatic cancer that has stopped responding to standard treatments. The goal is to see if the combo can shrink tumors or slow the disease. Researchers will also monitor side e…

This study tests a new software that combines MRI images with real-time ultrasound to help doctors more accurately target and biopsy suspicious prostate lesions. The goal is to improve early detection of aggressive prostate cancer and guide better treatment decisions. The study i…

This study tests whether metformin, a common diabetes drug, can prevent oral cancer in people with precancerous white or red patches in the mouth. 34 adults with these patches took metformin to see if it could reverse or stop the growth of abnormal cells. The goal is to find a sa…

This study tests a program to help Hispanic cancer survivors eat healthier and be more active. The goal is to reduce symptoms like pain, sleep trouble, and anxiety. About 187 survivors and their caregivers will take part. The program includes diet advice and physical activity tra…

This study tests whether daily exposure to green LED light can reduce chronic pain and improve quality of life. About 55 adults with pain from HIV, chemotherapy, or fibromyalgia will use a light device at home for 2 hours daily over 3 months. The goal is to see if light therapy c…

This study tests whether adding a second medicine (dexmedetomidine) to the standard nerve block medicine (dexamethasone) can make pain relief last longer after shoulder, foot, or ankle surgery. About 100 adults will receive either the combo or the standard block, then report thei…

This study looks at whether having a psychiatric service dog makes Prolonged Exposure Therapy work better for veterans with PTSD. About 216 veterans who already qualify for a service dog will take part. Researchers will measure PTSD symptoms using questionnaires and clinician int…

This study looks at whether putting weight on your ankle soon after surgery for a broken ankle helps you recover faster and return to work sooner. About 150 adults with certain types of ankle fractures will be randomly assigned to start walking right away or wait several weeks. T…

This study looks at whether trained service dogs can help reduce PTSD symptoms in military veterans over 15 months. About 150 veterans who already qualify for a service dog will be randomly assigned to get one or not. Researchers will track changes in PTSD severity, depression, a…

This study looks at whether specific voice exercises can improve voice quality in older adults with age-related voice changes (presbylarynx). Researchers will test 220 volunteers to understand how these exercises work and who benefits most. The goal is to ease symptoms like a wea…

This study tests whether a culturally adapted strength training program, done together with a caregiver, is feasible and beneficial for Hispanic prostate cancer survivors and their caregivers. The program involves remote group exercise classes over 3 months, with a 3-month follow…

This study looks at how many times a needle should be passed through a muscle during trigger point injections to best relieve myofascial pain. 300 adults with chronic muscle pain will be randomly assigned to receive 2, 10, or 20 needle passes per trigger point. Researchers will t…

This study looks at how green light exposure might help reduce pain. Researchers will measure brain and nerve activity in 30 healthy adults to understand the mechanism behind this effect. The goal is to learn how green light works, not to test a treatment.

This study looks at how different baby formulas affect the bacteria in a baby's gut compared to breast milk. Researchers will compare a standard formula, a new formula designed to be more like breast milk, and exclusive breastfeeding in 240 healthy, full-term infants. The goal is…

This study looks at how the brain handles two different tasks: remembering daily events (like when you last took medicine) and finding your way around. Researchers will use brain recordings and virtual reality in 15 healthy adults to understand these processes. The goal is to lea…

This study looks at how the brain's electrical signals and chemical levels change when people think, feel, or make decisions. Researchers will record brain activity in patients already undergoing brain surgery for epilepsy, while they play simple computer games or answer question…

This study follows about 120 children who received one booster dose of the HPV vaccine (Gardasil 9) to see how long their immune protection lasts. Researchers will measure antibody levels in blood samples taken at 4, 5, and 6 years after the first vaccine dose. The goal is to und…