Scientists probe brain waves to decode human thought
NCT ID NCT05273970
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study measures brain activity and chemical levels in people with epilepsy who already have electrodes implanted for medical reasons. Participants play simple computer games while their brain signals are recorded. The goal is to learn how the brain works during thinking and emotion, not to treat any condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2022
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 80 years, inclusive. * Patients who are candidates for electrode implantation due to pharmacologically intractable epilepsy, or other neurological/psychological disorders for which subdural electrode implantation may be clinically required for treatment. * Patients competent to give informed consent/assent for the research protocol and parents of children under 18 who are competent to give informed consent on behalf of the child. * Fluency in English (necessary for uniform cognitive testing). * Committee approved candidates for brain surgery. * Medications must be at stable doses for at least 1 month before surgery Exclusion Criteria: * Clinically significant cognitive dysfunction. * Terminal illness associated with \<12 month survival. * Contraindication to MRI imaging, e.g., morbid obesity, metallic devices such as cardiac pacemakers, some aneurysm clips, or shrapnel. * Current pregnancy or pregnancy planned during the course of the study. * Cognitive function less than 2 standard deviations below normal on preoperative neuropsychological testing
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Banner - University Medical Center, Phoenix campus
Phoenix, Arizona, 85006, United States
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