COGNITION

This study tests whether a daily dose of freeze-dried wild blueberry powder can improve blood sugar, blood pressure, thinking skills, and gut bacteria in women aged 20-65 who have prediabetes and are overweight. Participants will take the powder for a set period while researchers…

This study looks at whether eating wild blueberries can improve heart health, thinking skills, and gut bacteria in Black and White adults aged 45-65 with high blood pressure. Participants will eat blueberries and have their blood pressure, artery stiffness, and memory tested. The…

This study tests whether special reflective roof coatings can lower indoor temperatures and improve health in hot, low-income communities. About 3,200 adults in Burkina Faso, Mexico, India, Niue, and Fiji will have their roofs coated or not, and researchers will track heart rate,…

This study looks at whether eating peanuts every day can improve blood sugar, blood pressure, thinking skills, and gut health in adults with prediabetes. Researchers will enroll 72 racially diverse participants aged 20-59. Over 14 months, each person will follow both a peanut-eat…

This study tests an 18-week program where people with mild dementia and their family caregivers learn sport stacking (quickly stacking and unstacking cups) together. The goal is to see if this fun, at-home activity improves thinking, mood, and quality of life for both. About 144 …

This study tests a 3-month exercise program for people with mild cognitive impairment (early memory loss) due to Alzheimer's. Participants will do exercises that combine physical and mental tasks twice a week. Researchers want to see if this improves walking, balance, and thinkin…

This study tests whether a daily dietary supplement can improve memory, thinking, and emotional well-being in healthy adults aged 55 and older. Sixteen participants will take the supplement for 45 days and complete memory and mood tests at the start and end. The goal is to see if…

This study looks at whether adding breathing exercises to balance training can improve thinking skills in people aged 65 and older. Participants will do 30 minutes of balance exercises plus 15 minutes of breathing exercises twice a week for 8 weeks. The goal is to see if differen…

This study tests whether a special type of dynamic lighting can improve sleep, daily rhythms, and overall well-being in frail older adults (over 65) who are in the hospital. Researchers will measure changes in melatonin levels and sleep patterns. The goal is to see if adjusting l…

This study tests whether giving a daily prebiotic (a type of fiber) to 3-5 year olds who don't eat enough fiber can improve their mood, sleep, thinking skills, and gut health. About 106 children will take either a prebiotic or a placebo for several weeks. Parents will report on t…

This study looks at whether a single dose of a supplement containing American Ginseng can improve attention and brain function in healthy young adults aged 18 to 40. Participants will take the supplement and then complete memory and thinking tests over 6 hours, with blood samples…

This study looks at whether adding nuts to the diet can improve mental health in young adults. Researchers will measure changes in depression, anxiety, stress, memory, and thinking skills in 135 university students aged 18 to 25. Participants will eat nuts or follow their usual d…

This study explores whether immersive virtual reality exercise therapy can reduce pain, improve shoulder function, sleep, and thinking skills in people with mild to moderate frozen shoulder (grade 1-2). About 36 adults aged 18-64 who are new to physiotherapy will use VR headsets …

This study tests whether taking ETAS® daily for 12 weeks can improve memory, mood, and sleep in healthy adults aged 60 to 80 who have mild memory complaints. Participants will take either the supplement or a placebo and undergo brain scans and thinking tests. The goal is to see i…

This study looks at whether adding a whey protein-enriched milk fat globule membrane supplement to a high-fat meal can improve heart and brain health in postmenopausal women who are overweight and at moderate risk for heart disease. Sixteen women will attend two full-day visits, …

This study tests whether a special thinking and attention training program works as well when done via video call as it does in person. It is for veterans who have both a mild traumatic brain injury and PTSD and struggle with focus and memory. The goal is to see if the program im…

This study tests whether using a safe, low-current brain stimulation device at home for 6 months can improve thinking and walking in older adults (ages 65-90) who have memory concerns and walk slowly, putting them at higher risk for dementia. Participants will use a headset for 2…

This study is testing whether a smartphone app can help firefighters improve their sleep, thinking, and overall health. About 50 firefighters will use the app and report on their sleep habits. The goal is to see if the program is easy to use and helpful for this group.

This study looks at whether taking the amino acid L-serine, alone or with strength training, can improve memory, thinking, and physical fitness in healthy older adults. Researchers will test 126 people aged 65-85 over 48 weeks using cognitive tests, blood work, and brain scans. T…

This study looks at how a single dose of modafinil changes decision-making and brain activity in healthy adults. Researchers hope to learn more about psychosis spectrum disorders like schizophrenia. Participants will take modafinil, play computer brain games, and wear an EEG cap …

This study looks at whether a special nutrition shake given after surgery can help older adults (70+) regain their physical and mental abilities faster. Half of the 100 participants will receive the shake daily for 30 days, while the other half gets standard recovery advice. The …

This study looks at how obstructive sleep apnea (OSA) affects thinking skills and empathy in children aged 3 to 12. Researchers will compare surgical and medication treatments for mild OSA and track changes over 12 months. They will also look for brain wave patterns that might sh…

This study aims to create a large, diverse group of 1,000 older adults (age 60+) to help researchers better understand Alzheimer's disease. Participants, who may be healthy, have mild memory problems, or have Alzheimer's, will have yearly check-ups including memory tests, brain s…

This study watches 100 adults with treatment-resistant depression who are taking esketamine nasal spray as part of their normal care. Researchers want to see how well it works, who responds best, and how it affects daily life, work, and mood. They will also look at genetic and br…

This study tests whether a home-based mobile app can help 3-4 year olds who currently meet few movement guidelines improve their physical activity, sleep, and screen time. About 80 children and their parents will use the app for 12 weeks, with researchers tracking changes using a…

This study looks at how long-term marijuana use affects brain inflammation and thinking abilities in people with HIV. Researchers will use brain scans and blood tests to measure changes in brain health. The goal is to understand the effects, not to test a new treatment. About 220…

This study looks at whether low magnesium in the blood is linked to thinking problems after a stroke. Researchers will measure magnesium levels and test memory, orientation, and other cognitive skills in 80 stroke patients over several weeks. The goal is to understand if magnesiu…

This pilot study tests whether shining near-infrared light on the head (transcranial photobiomodulation) can improve blood flow and thinking in older adults. Thirty participants aged 21-85 will receive either active or sham treatment every other day for 4 weeks. Researchers will …

This study will follow 874 children aged 3 to 5 for one year to understand how using tablets and smartphones affects their thinking, health, and school readiness. Parents will install an app that tracks device use, and researchers will measure children's memory, attention, langua…

This study tests a group program that teaches emotion regulation and values to help people with depression who have recently attempted suicide. The goal is to improve their ability to handle daily activities and quality of life. Researchers will also use brain scans to see how th…

This study looks at how healthy adults think ahead when making decisions. Volunteers will play a game similar to Connect Four while researchers record their brain activity and eye movements. The goal is to understand the brain processes behind multi-step planning. This is an obse…

This study looks at how haloperidol, an antipsychotic medication, may interfere with insulin's normal action in the brain. Insulin helps control blood sugar and supports brain function, but long-term use of haloperidol can lead to weight gain and diabetes. Researchers will give h…