COGNITION

This study is testing whether eating freeze-dried wild blueberry powder daily for six months can help improve heart health, gut bacteria, and memory in Black and White adults with high blood pressure. Researchers will compare the effects of the blueberry powder to a placebo. The …

This study is testing whether a 6-month, at-home brain stimulation treatment can help improve memory, thinking, and walking in older adults who show early signs of increased dementia risk. Participants will use a non-invasive device that delivers a mild electrical current to the …

This study is testing whether a special exercise program can help people with early memory loss due to Alzheimer's disease. Researchers want to see if exercises that combine physical and mental tasks can improve walking, balance, and thinking skills better than regular exercise o…

This small pilot study is testing whether taking whey protein supplements can help older adults who are starting to show signs of frailty. Researchers want to see if the protein improves brain antioxidant levels, measured by MRI scans, and also helps with strength, balance, and t…

This study is testing whether a home-based mobile app can help parents improve their preschooler's daily movement habits. Researchers want to see if the app helps more 3-4 year olds meet recommended targets for physical activity, sleep, and limited screen time. They will compare …

This global study is testing whether painting roofs with special reflective coatings can keep homes cooler and prevent heat-related health problems. Researchers are working with 3,200 people in five hot climate regions where housing conditions make residents especially vulnerable…

This study is testing whether eating a mix of nuts for six months can help improve mental health and thinking skills in young adults. Researchers will recruit 135 university students aged 18-25 to see if the nuts reduce symptoms of depression, anxiety, and stress, and improve mem…

This study is testing whether using immersive virtual reality (VR) games for shoulder exercises is more effective than standard physical therapy for people with frozen shoulder. Researchers will compare two groups of patients over six weeks to see if the VR approach better reduce…

This study is testing whether taking an amino acid supplement called L-serine, either by itself or combined with strength training, can help improve mental sharpness, brain function, and physical fitness in healthy older adults. Researchers will enroll 126 men and women aged 65 t…

This study is testing whether a daily nutrient shake helps older adults recover their physical strength and thinking skills after major surgery. Half of the 100 participants will receive the shake for one month after leaving the hospital, while the other half will receive standar…

This study is testing whether a phone app and monthly coaching calls can help firefighters get better sleep. Fifty firefighters will try the app for three months, tracking sleep and learning healthy habits, while others receive basic sleep information. The main goal is to see if …

This study is testing whether a daily liquid dietary supplement can improve memory, focus, and mood in healthy adults aged 55 and older. Participants will take the supplement or a control drink for 45 days and complete memory and mood tests at the start and end. The goal is to se…

This study is testing a special exercise program called 'sport stacking' (quickly stacking and unstacking cups) for people with mild dementia and the family members who care for them. The goal is to see if doing these activities together can help improve the person's thinking ski…

This study is testing whether a single dose of an American ginseng supplement can improve attention and mental performance in healthy young adults. Researchers will give 200 participants either the supplement or a placebo and measure their focus, memory, and reaction time over 6 …

This study is testing whether special 'dynamic' lighting in hospital rooms can help improve sleep and daily rhythms for elderly patients. It will involve 300 patients over age 65 who are hospitalized. Researchers will compare patients in rooms with the special lighting to those i…

This study is testing whether a brain training program that combines strategy coaching with attention exercises can help veterans with mild brain injury and PTSD improve their thinking skills and ability to handle daily tasks. Researchers are comparing whether delivering this tra…

This study aims to understand how using tablets and smartphones affects the development and health of young children. Researchers will track 3-to-5-year-olds in England for one year, measuring screen time with a special app and assessing skills like memory, self-control, and phys…

This study is observing 100 adults with treatment-resistant depression who are already prescribed esketamine nasal spray in real-world settings. Researchers are tracking how well it works, who responds best, and how it affects people's daily lives and functioning. The goal is to …

This study aims to build a detailed database of information to help scientists understand Alzheimer's disease and related memory problems. It will enroll 1,000 adults aged 60 and older, including those with and without memory concerns. Participants will undergo annual check-ups, …

This study aims to understand how antipsychotic medications, specifically haloperidol, might block insulin's normal action in the brain. Researchers will enroll 35 healthy adults to measure brain activity and metabolic markers before and after receiving insulin through a nasal sp…

This study aims to understand how obstructive sleep apnea (OSA) affects children's thinking skills and ability to understand others' feelings. Researchers will observe 150 children, aged 3-12, for one year to see how their brains develop. They will compare outcomes for kids who g…

This study aims to understand how decision-making works in conditions like schizophrenia. Researchers are giving a single dose of a medication called modafinil to healthy volunteers and measuring changes in their brain activity and performance on computer 'brain games.' The goal …

This study is testing whether a non-invasive light therapy helmet can improve how the brain regulates blood flow during thinking tasks and if this helps memory and thinking skills in older adults. Researchers will compare the real light treatment to a fake one in 30 participants …

This study aims to understand if low levels of magnesium in the blood are connected to memory and thinking problems people often experience after a stroke. Researchers will follow 80 stroke patients, measuring their magnesium levels and testing their thinking skills at several po…

This study is testing whether giving young children a daily prebiotic fiber supplement for 8 weeks can improve their thinking skills, behavior, and the balance of bacteria in their gut. It will involve about 106 healthy children aged 3-5 who don't eat much fiber. Researchers will…

This study aims to understand how the brain helps people plan multiple steps ahead. Healthy adult volunteers will play a strategy game similar to Connect Four while researchers measure their brain activity using scanners. The goal is to learn how people mentally simulate future m…

The goal of this interventional clinical trial is to investigate the effects of breathing exercises added to balance training on cognitive function in individuals aged 65 years and older. The main questions it aims to answer are: Do breathing exercises affect cognition? Do diff…