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Real-World study seeks to unlock Esketamine's secrets for tough depression

NCT ID NCT07146503

First seen Oct 31, 2025 · Last updated May 24, 2026 · Updated 30 times

Summary

This study watches 100 adults with treatment-resistant depression who are taking esketamine nasal spray as part of their normal care. Researchers want to see how well it works, who responds best, and how it affects daily life, work, and mood. They will also look at genetic and brain markers to predict success. The goal is to make treatment more personal for people who haven't gotten better with other antidepressants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ASST Fatebenefratelli Sacco

    RECRUITING

    Milan, 20157, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ASST Pavia

    RECRUITING

    Pavia, 27100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Csm Dds 8

    RECRUITING

    Genova, Ge, 16158, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ospedale Policlinico San Martino

    RECRUITING

    Genova, Ge, 16132, Italy

    Contact Email: •••••@•••••

  • Università di Chieti

    RECRUITING

    Chieti, 66100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.