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Simple breathing workout may ease strain on heart in lung condition

NCT ID NCT06931886

Symptom relief Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether six weeks of daily breathing exercises against resistance can improve heart and lung function in people with pulmonary hypertension. Four participants will do 30 resisted breaths per day, five days a week. Researchers will measure changes in heart pressure, blood flow, and exercise capacity using tests already scheduled as part of routine care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
inspiratory muscle strength training (breathing exercises against resistance)
What this could lead to
If it works, this could point toward a simple, drug-free way to improve exercise tolerance and heart function in people with pulmonary hypertension.
What could go wrong
This is a very small pilot study with only 4 participants, so results may not apply to everyone. The training is short (6 weeks) and may not produce lasting benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 4 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosed with PH defined by clinical guideline criteria * Must already be scheduled for a clinical assessment of their PH within 8 weeks of enrolling in the study. * Must have undergone an assessment of their PH in the last 18 months with no major changes in PH management or medication within that period. Exclusion Criteria: * Current smoker or have smoked in the last 10 years * Unable or unwilling to undergo routine functional testing of their PH (i.e., 6-minute walk distance). * Presence of significant cardiovascular or respiratory conditions other than PH, including but not limited to: * Chronic obstructive pulmonary disease * Severe asthma * Severe ischemic heart disease * Left-sided heart failure * History of a major cardiovascular event, such as a myocardial infarction or stroke, within the last 6 months * Individuals with an implanted pacemaker or other significant cardiac devices * History of neurological, respiratory, head and neck, or thoracic surgeries, or conditions such as a collapsed lung or perforated eardrum * Pregnant individuals or those actively trying to become pregnant * Individuals with any of the following: chronic laryngitis, chronic bronchitis, emphysema, pneumonia, tuberculosis, chronic cough, extremely high blood pressure (\>170/100), neurological problems, scoliosis, organ transplants, HIV or other immunocompromising conditions, or autoimmune disease.

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Conditions

The condition(s) this trial relates to.

pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pulmonary hypertension

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  3. A doctor treating you

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Contacts and locations

Locations

  • University of Arizona

    Tucson, Arizona, 85711, United States

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