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Can a diabetes drug stop oral cancer before it starts?

NCT ID NCT05237960

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 33 times

Summary

This study tests whether metformin, a common diabetes drug, can prevent oral cancer in people with precancerous white or red patches in the mouth. 34 adults with these patches took metformin to see if it could reverse or stop the growth of abnormal cells. The goal is to find a safe, low-cost way to stop oral cancer from developing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • British Columbia Cancer Agency

    Vancouver, British Columbia, V5Z 4E6, Canada

  • Dalhousie University

    Halifax, Nova Scotia, B3H 4R2, Canada

  • Emory University Hospital/Winship Cancer Institute

    Atlanta, Georgia, 30322, United States

  • Louisiana State University

    Lafayette, Louisiana, 70503, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • NYU College of Dentistry

    New York, New York, 10010, United States

  • UC San Diego Medical Center - Hillcrest

    San Diego, California, 92103, United States

  • University of Arizona Cancer Center-North Campus

    Tucson, Arizona, 85719, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Minnesota/Masonic Cancer Center

    Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.