Common diabetes drug tested to stop mouth cancer before it starts

NCT ID NCT05237960

Ongoing Prevention Sponsor: University of Arizona Source: ClinicalTrials.gov ↗

Summary

This study is testing whether metformin, a common diabetes medication, can prevent oral cancer in people who have pre-cancerous white or red patches in their mouth. Participants with these patches were randomly assigned to take either metformin or a placebo pill daily for 24 weeks. Researchers are checking if the drug causes the patches to shrink or disappear, which could mean it's preventing cancer development.

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Contacts and locations

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Locations

British Columbia Cancer Agency

Vancouver, British Columbia, V5Z 4E6, Canada
Dalhousie University

Halifax, Nova Scotia, B3H 4R2, Canada
Emory University Hospital/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Louisiana State University

Lafayette, Louisiana, 70503, United States
Moffitt Cancer Center

Tampa, Florida, 33612, United States
NYU College of Dentistry

New York, New York, 10010, United States
UC San Diego Medical Center - Hillcrest

San Diego, California, 92103, United States
University of Arizona Cancer Center-North Campus

Tucson, Arizona, 85719, United States
University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States
University of Minnesota/Masonic Cancer Center

Minneapolis, Minnesota, 55455, United States

Conditions

Explore the condition pages connected to this study.

ERYTHROPLAKIA ORAL LEUKOPLAKIA