University Of Alberta

This study tested whether doxycycline, an antibiotic, can prevent further heart damage after a heart attack. 174 adults who had a severe heart attack took doxycycline or a placebo twice daily for one week. Three months later, researchers used MRI scans to check heart structure an…

This study looked at whether it is safe and helpful to reduce blood pressure medications in frail older adults living in long-term care. Over 500 participants with low blood pressure were randomly assigned to either have their medications slowly reduced or to continue usual care.…

This study tested a home-based lifestyle program for adults aged 50-85 with type 2 diabetes and chronic kidney disease. The program focused on healthier eating and exercises to prevent frailty, which causes muscle weakness and makes daily tasks harder. 120 participants were assig…

This study looked at whether special neck exercises could help women with long-term jaw pain (temporomandibular disorders, or TMD). 113 women were split into two groups: one did neck motor control exercises for 8 weeks, and the other received a placebo treatment. The goal was to …

This study compared robot-assisted walking training (Lokomat) with standard physical therapy for 68 children with cerebral palsy aged 5-18. The goal was to see which approach improves walking skills, balance, and quality of life. Results help families and doctors choose the best …

This study tested whether a mobile app exercise program is practical and helpful for women with breast cancer undergoing chemotherapy. 32 women participated, doing guided exercises and education through the app. The goal was to see if it improves arm function, fitness, and qualit…

This study tested whether an AI-powered social robot could help children aged 5 to 11 feel less pain and distress during an IV insertion. The robot used distraction techniques, like cognitive-behavioral therapy, to support the child during the procedure. Researchers compared the …

This study looked at whether giving children with migraine just intravenous (IV) fluids in the emergency department can ease their headache pain. 46 children took part. Researchers measured pain, nausea, and whether more medicine was needed later. The goal was to see if hydration…

This study tested a cream called Nefopam to see if it could prevent or reduce raised, red, and itchy scars in burn patients. About 50 adult burn patients had small, controlled cuts made on their hips. One cut was treated with the Nefopam cream and the other with a placebo cream. …

This study tested a 12-week online program that combines gentle movement, breathing exercises, and coping skills for adults with chronic conditions like heart failure, liver disease, or cancer. The goal was to see if it could reduce anxiety and depression. Over 800 people took pa…

This study looked at whether a short-term, plant-based low-calorie diet (called a fasting mimicking diet) could improve depressive symptoms in people with inflammatory bowel disease (IBD). 42 adults with IBD and mild-to-moderate depression completed three 5-day diet cycles. Resea…

This study looked at whether adding a digital remote monitoring system to a standard lung rehabilitation program is practical for people with COPD. 78 participants were split into two groups: one got the standard program, and the other also used a digital device to track their he…

This study tested whether a steroid injection into the thumb joint can reduce pain and improve function in people with thumb arthritis. 61 adults with thumb arthritis received either a steroid shot or a placebo (saline) shot, both with numbing medicine. Researchers measured pain …

This study tested a 10-week online wellness program for women with primary biliary cholangitis (PBC), a chronic liver disease that causes fatigue, itching, brain fog, and emotional distress. The program included guided breathing, meditation, and gentle movement, plus optional nut…

This study tested whether metformin, a common diabetes medicine, can help improve language, behavior, and weight problems in people with fragile X syndrome. 125 people aged 6 to 35 took either metformin or a placebo for 4 months. Researchers measured changes in spoken language an…

This study looked at whether wearing advanced compression sleeves during progressive resistance exercises can help reduce lymphedema (arm swelling) in women who had breast cancer surgery. 60 women with mild to moderate chronic lymphedema participated in a 12-week program. The goa…

This study tested whether interval training or moderate continuous exercise could improve exercise capacity in 47 adults with congenital heart disease. Participants were randomly assigned to one of two exercise programs or usual care. The main goal was to see if exercise training…

This study looked at whether a short burst of electrical stimulation after surgery can help nerves in the arm grow back better. 136 adults with severe nerve injuries were randomly assigned to receive either the electrical stimulation or standard care. Researchers measured hand fu…

This study looked at whether a mix of in-person and online physiotherapy sessions is practical for children aged 4 to 17 with acute lymphoblastic leukemia. Ten children and their parents tried the program, which used an online platform for exercises and education. The goal was to…

This study looked at how speech production helps reading in adults with and without dyslexia. 56 adults completed reading tasks while doing things like sucking a lollipop or having their mouth numbed. The goal was to see if changing speech feedback affects reading accuracy and br…

This pilot study tested a protocol for a future Canada-wide trial. It looked at whether using a patient's own blood during heart surgery reduces bleeding, the need for donated blood products, and complications. 64 adult heart surgery patients at high risk for bleeding were random…

This study tested whether specially designed tablet games, called VibrantMinds, can measure and improve cognitive skills in older adults with mild cognitive impairment or dementia. 26 participants aged 65 and older played the games, and researchers tracked changes in thinking, mo…

This study looked at how a person's daily activity and brain imaging right after a stroke can help create a personalized rehabilitation plan. Researchers worked with 55 stroke survivors to see if reducing sitting time and increasing movement improves walking and daily function. T…

This study looked at whether having dialysis patients regularly fill out questionnaires about their symptoms and well-being helps them talk better with their doctors and nurses. About 4,000 adults on dialysis in Alberta and Ontario took part. Some patients filled out symptom-focu…

This study tested a new gluten-free food guide designed to help children and teens with celiac disease eat healthier. 40 newly diagnosed participants used the guide or standard care for 6 months. Researchers measured diet quality and how well they stuck to the gluten-free diet.

This study gathered information from 32 people to better understand cytolytic vaginosis, a poorly understood condition. Researchers looked at risk factors, symptoms, and how to diagnose it, and also tested whether baking soda vaginal washes work as a treatment. The goal is to hel…

This study tested a new way to manage serious staph bloodstream infections in Alberta hospitals. A central team of experts reviewed each case and gave treatment recommendations based on best practices. Researchers compared care before and after the new model was introduced, looki…

This study looked at how much waste and carbon dioxide different types of anesthesia produce during wrist fracture surgery. 30 adults having wrist surgery were assigned to receive general anesthesia, regional anesthesia, or both. Researchers collected and weighed the waste from e…

This study tested whether a smartphone app (MyREADY Transition CHD) helps 16-17 year olds with congenital heart disease learn to manage their own health as they move from pediatric to adult care. 207 teens used the app for 18 months or had a one-time talk with a nurse. Researcher…

This study looked at whether using common asthma inhalers for 4 weeks can change how blood vessels work in healthy people aged 18 to 40. Participants used either Ventolin, Symbicort, or a placebo inhaler and had tests like lung function, exercise, and ultrasound of arm arteries. …

This study looked at whether eating at least two eggs a day can help cancer patients regain lost muscle and improve their nutrition after finishing treatment. Only 2 people took part, and half started the egg diet right away while the other half waited 4 weeks. The goal was to se…

This study tested two methods for positioning the jaw when making a dental sleep appliance for obstructive sleep apnea. Eleven adults tried both the standard forward-jaw method and a technique using speech sounds. The goal was to see if the speech method works just as well for ma…

This study looked at whether the design of a common ADHD screening questionnaire influences how people answer. Researchers tested different versions of the form with 587 adults in a family medicine clinic. The goal was to see if shading or grouping certain answer choices made it …

This study tested whether a breathing technique called volume-targeted ventilation is practical for very premature infants (born between 23 and 28 weeks) who need help breathing right after birth. 52 babies were randomly assigned to receive either standard pressure-based breathin…