University Of Alberta
Clinical trials sponsored by University Of Alberta, explained in plain language.
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Could talking help position sleep apnea devices better?
Disease control CompletedThis study compared two methods for positioning dental appliances used to treat sleep apnea. Researchers tested whether using speech sounds to position the jaw works as well as the traditional method of pushing the jaw forward. The study involved 11 adults with sleep apnea who ne…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Apr 03, 2026 21:41 UTC
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Diabetes drug shows promise for genetic brain disorder
Disease control CompletedThis study tested whether metformin, a common diabetes medication, could help people with Fragile X syndrome. 125 participants aged 6 to 35 took either metformin or a placebo for 4 months. Researchers measured changes in language skills, behavior problems, and weight to see if th…
Phase: PHASE2 • Sponsor: University of Alberta • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Can a smartphone app better prepare teens with heart conditions for adult life?
Disease control CompletedThis study tested whether a mobile app or a one-time meeting with a nurse was better at preparing teenagers with congenital heart disease to manage their own health as they move from pediatric to adult healthcare. Over 200 teens aged 16-17 used either the educational app for 18 m…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Breathing breakthrough for tiniest babies?
Disease control CompletedThis small pilot study tested whether a newer method of helping premature babies breathe right after birth is practical to use. It compared a volume-targeted approach to the standard pressure-guided method during initial care in the delivery room. The goal was to see if the newer…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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COPD patients test At-Home digital monitoring in rehab program
Disease control CompletedThis study tested whether adding a digital remote monitoring system to a standard COPD rehabilitation program was practical and acceptable for patients and staff. 78 people with COPD were split into two groups: one used the digital monitoring alongside rehab, and the other did re…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Study challenges routine blood pressure pills for the frail elderly
Disease control CompletedThis study tested whether carefully reducing or stopping blood pressure medication is safe and beneficial for frail older adults living in nursing homes who already have low blood pressure. Over 500 residents were randomly assigned to either have their medications reduced or to c…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Heart surgery patients try using their own blood to avoid donor risks
Disease control CompletedThis small pilot study tested a new method for heart surgery patients at high risk of bleeding. Researchers wanted to see if collecting and giving patients their own blood back after surgery works as well as the standard method of using donated blood products. The goal was to che…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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Gut-Friendly fasting diet tested to lift mood in bowel disease patients
Symptom relief CompletedThis study tested whether a special plant-based, low-calorie 'fasting mimicking' diet could reduce depression symptoms in people with Crohn's disease or ulcerative colitis. 42 adult participants with mild depression tried three cycles of the 5-day diet, followed by normal eating.…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 03, 2026 21:40 UTC
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Strength training in special sleeves may ease Post-Cancer swelling
Symptom relief CompletedThis study tested a new 12-week program for women with chronic arm swelling (lymphedema) after breast cancer surgery. Researchers wanted to see if combining strength training exercises with wearing a special compression sleeve could safely reduce swelling and improve arm function…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Phone-Based fitness program aims to ease chemo side effects
Symptom relief CompletedThis study tested whether a 10-week exercise program delivered through a mobile app is a practical way to help breast cancer patients during chemotherapy. Researchers compared a general exercise program to one that also included specific physiotherapy for the arms and shoulders. …
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Can training your neck calm your jaw pain? new study investigates
Symptom relief CompletedThis study tested whether a specific 8-week program of neck exercises could help women with chronic jaw pain (temporomandibular disorders, or TMD). Researchers wanted to see if the exercises reduced pain and disability, and if they also caused changes in the brain related to pain…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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Egg diet trial aims to rebuild cancer Patients' bodies
Symptom relief CompletedThis small study tested whether eating at least two eggs daily for eight weeks could help cancer patients recover after finishing chemotherapy. Researchers wanted to see if this simple food-based approach could help patients meet their protein needs to rebuild muscle, improve str…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 31, 2026 12:10 UTC
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Simple IV fluids tested as first step for Kids' severe migraines
Symptom relief CompletedThis study looked at whether giving children intravenous (IV) fluids alone could help reduce severe migraine pain when they visit the emergency department. Researchers wanted to see if the expectation of getting medication influenced pain relief. The goal was to find a simpler, f…
Phase: PHASE1, PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 30, 2026 14:33 UTC
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Can virtual and In-Person therapy help kids beat Cancer's side effects?
Symptom relief CompletedThis study tested whether a 12-week physical therapy program, delivered partly in-person and partly online, is practical and acceptable for children with acute lymphoblastic leukemia. The goal was to help kids manage the muscle and bone side effects of cancer treatment. Researche…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Can simple surveys ease the burden of dialysis?
Symptom relief CompletedThis large study tested whether regularly asking dialysis patients about their symptoms and quality of life could improve their care. Nearly 4,000 patients across Canada were involved. Dialysis clinics were assigned to either use specific symptom surveys, general health surveys, …
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Robot buddy fights Kids' fear of needles
Symptom relief CompletedThis study tested whether a friendly, AI-enhanced robot could help distract children aged 5-11 during needle procedures like IV insertions. The goal was to see if interacting with the robot could reduce the child's pain, fear, and distress compared to standard care alone. Researc…
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Mar 10, 2026 12:53 UTC
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Do common asthma inhalers harm your heart? study investigates
Knowledge-focused CompletedThis study aimed to understand whether long-term use of common asthma inhalers might affect heart and blood vessel health, even in people without asthma. Researchers enrolled 81 healthy young adults and had them use either real inhalers or a placebo for four weeks. They measured …
Phase: PHASE1 • Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Can numbing your tongue help you read? scientists test surprising link
Knowledge-focused CompletedThis study investigated whether the physical act of speaking is connected to reading ability, especially in adults with dyslexia. Researchers tested 56 adults (with and without dyslexia) by having them read words while performing different mouth tasks, like sucking a lollipop or …
Phase: PHASE4 • Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:56 UTC