Could a common diabetes drug help with fragile x symptoms?
NCT ID NCT03862950
First seen Jan 09, 2026 · Last updated Apr 30, 2026 · Updated 16 times
Summary
This study tested whether metformin, a diabetes medicine, can improve language, behavior, and weight problems in people with fragile X syndrome. 125 participants aged 6 to 35 took either metformin or a placebo for 4 months. Researchers measured changes in spoken language and behavior to see if the drug helped.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Sainte-Justine
Montreal, Quebec, H3T 1C5, Canada
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University of Alberta
Edmonton, Alberta, T6G 2E1, Canada
Conditions
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