INTELLECTUAL DISABILITY

This study tests whether metformin, a diabetes medication, can help adults with intellectual disability who have gained weight from antipsychotic drugs. About 100 participants will receive either metformin or a placebo for several months. The goal is to see if metformin leads to …

This study tests whether adding hands-on cooking classes to a standard weight loss program helps young adults (ages 18-35) with mild-to-moderate intellectual disabilities lose more weight and maintain that loss over 24 months. Participants will be split into two groups: one gets …

This study tests a program called PACE that helps adults with intellectual disability become more physically active. About 120 adults, their caregivers, and coaches will take part. The program focuses on increasing daily steps and moderate-to-vigorous activity to improve overall …

This study aims to create and test a simple scale that caregivers can use to spot common eye problems in adults with intellectual disability. Currently, no such tool exists, leading to delayed diagnosis. Researchers will work with 1,400 caregivers and adults with intellectual dis…

This study follows up to 150 people with MEHMO syndrome or related disorders to track how the disease progresses over time. Researchers will collect medical history, imaging, and lab samples to identify biological markers. The goal is to better understand these conditions and dev…

This study follows 1,000 people with certain genetic changes linked to brain development issues like autism, intellectual disability, and seizures. Researchers collect medical records, school reports, and test results to see how these genes affect thinking, movement, and behavior…

This study looks at bladder and bowel problems in children aged 5 to 12 with intellectual disabilities and compares them to typically developing children. Researchers want to understand how these issues affect the child's participation in daily activities and the family's quality…

This study tests a job support program called IPS-AUT for autistic adults aged 18-40 who are not currently working but want a job. The program helps people find and keep competitive jobs in the community. Researchers will check if the program is practical, acceptable, and effecti…

This study tests whether playing digital brain games can improve visual memory and thinking skills in young adults (ages 18-35) with mild to moderate intellectual disabilities. Sixty participants will be split into two groups: one plays games from the MentalUP app, the other cont…

This study looks at whether letting people with intellectual or developmental disabilities use their preferred way to communicate (like a touch talker or picture cards) helps them stick with positive behaviors and reduces the chance of challenging behaviors returning. About 60 pa…

This study tests whether a one-time online lesson can improve how researchers think about and include people with disabilities in their studies. About 200 researchers will take the course, and their knowledge and attitudes will be measured before and after. The goal is to make re…

This study compares brain activity and pain responses between people with intellectual disability (ID) and healthy volunteers. Participants aged 8 to 30 will receive mild heat, cold, brushing, or electrical stimuli while wearing a brain-monitoring cap. The goal is to better under…