Tongji Hospital

This study is testing whether a combination of two drugs—lenvatinib (a pill) and a PD-1 inhibitor (an immunotherapy given by IV)—can help control advanced solid tumors that have a specific genetic feature called '11q13 amplification.' The main goals are to see if tumors shrink or…

This study is testing whether a combination of targeted drugs (toripalimab and RC48-ADC) plus radiation can effectively treat muscle-invasive bladder cancer while allowing patients to keep their bladder. The trial will enroll 45 adults with HER2-positive bladder cancer who have a…

This study is testing a new combination treatment for people with advanced liver cancer (hepatocellular carcinoma) who also have high blood pressure in their liver (portal hypertension) due to cirrhosis. The treatment combines a minimally invasive procedure (TACE) with three drug…

This study is testing a new oral medication called ivarmacitinib for people with moderate-to-severe rheumatoid arthritis (RA) who haven't gotten enough relief from common first-line drugs like methotrexate. It aims to see if this pill can better control the disease and reduce sym…

This early-phase study is testing a new cell therapy called AZD0120 in adults with end-stage kidney disease who are waiting for a transplant but have high levels of antibodies that make finding a compatible donor very difficult. The goal is to see if this therapy can safely reduc…

This early-phase study is testing a new type of cell therapy for adults with acute myeloid leukemia (AML) that has come back or hasn't responded to other treatments. The therapy involves modifying a patient's own immune cells to recognize and attack two specific markers found on …

This study aims to find the best combination treatment for advanced liver cancer that cannot be removed by surgery. It will compare two different local drug delivery methods (TACE and HAIC), each combined with two other cancer drugs, in about 364 patients. The main goal is to see…

This study is testing if a smartwatch with artificial intelligence (AI) can help people recover after a heart attack. It will see if the watch, worn for 3 months during rehab, can better monitor health, improve quality of life, and reduce return trips to the hospital compared to …

This early-stage study is testing a new cell therapy called ACE1831 for people with severe systemic lupus erythematosus (SLE) that has not improved with standard treatments. ACE1831 is made from immune cells (gamma delta T cells) donated by healthy people. The main goals are to s…

This early-phase study is testing a new type of CAR-T cell therapy designed to attack two common targets (CD19 and CD22) on cancer cells. It aims to see if this approach is safe and effective for adults with B-cell acute lymphoblastic leukemia or non-Hodgkin lymphoma that has com…

This study aims to find out if the diabetes medication glimepiride can help people who have both type 2 diabetes and chronic heart failure. It will involve about 1,500 participants who will be randomly assigned to receive either glimepiride or a placebo (a dummy pill) for three y…

This study aims to see if an artificial intelligence (AI) model can better identify which liver cancer patients need immunotherapy after surgery to prevent the cancer from coming back. It will follow 300 patients who have had their liver tumors surgically removed. The AI will ana…

This study aims to see if an oral medicine made from bezoar, a traditional ingredient, can help people recover from a brain bleed (intracerebral hemorrhage), a severe type of stroke. Researchers will give the medicine to 300 adults who recently had a small to moderate brain bleed…

This study aims to test a new artificial intelligence (AI) tool designed to help doctors tell the difference between common, non-cancerous uterine fibroids and a rare, aggressive cancer called uterine sarcoma using MRI scans. It will involve 500 women who are already scheduled fo…

This study is testing a new blood test to see if it can accurately tell when liver cancer returns after a patient's initial treatment. Researchers will enroll 162 adults who have had or will have treatment like surgery or ablation. They will compare the results of this new test a…

This study is testing a blood test that looks for tiny amounts of leftover cancer DNA after liver cancer surgery. Researchers want to see if this test can better predict which patients' cancer is likely to return. The study will also help identify which patients might benefit mos…

This study aims to see if a new Chinese herbal formula called TJAOA103 can safely relieve symptoms of genitourinary syndrome of menopause (GSM), such as vaginal dryness, pain, and urinary issues. About 113 women aged 45-70 with moderate to severe symptoms will take the herbal for…

This study is testing a new method to manage pain after lung surgery. It combines a nerve-block injection near the ribs with a patient-controlled pain medication pump. The goal is to provide better pain relief with fewer side effects like nausea, helping patients recover more com…

This study aims to see how well a pain medication called osellidine works for women having outpatient hysteroscopy surgery. Researchers will observe and compare osellidine to standard pain treatments, focusing on pain control, side effects, and how quickly patients recover. The g…

This study is testing if a virtual reality (VR) mindfulness program can help patients feel less anxious and experience less pain during minor vascular surgeries done with local anesthesia. Researchers will enroll 160 patients, with half using the VR program and half receiving sta…

This study aims to observe and understand how a group of diseases where the immune system attacks the nervous system behave in real life. It will follow 1,550 patients diagnosed with conditions like multiple sclerosis or myasthenia gravis over time. The goal is to collect long-te…

This study looks back at medical records to see if keeping patients at a specific depth of anesthesia during short ear, nose, and throat surgeries leads to better recovery. Researchers will compare two groups based on their brain monitor readings during the procedure. The goal is…

This study aims to test and improve a computer model designed to predict how uterine fibroids affect a woman's chances of getting pregnant. It will follow over 7,000 women with fibroids who want to conceive, tracking their pregnancy outcomes. The goal is to create a reliable tool…

This study looks back at medical records to see if eating a low-carbohydrate diet is linked to better survival for women with a specific type of ovarian cancer who are on a standard maintenance therapy. Researchers will compare the outcomes of about 600 patients who had different…