Tongji Hospital

This study tests whether baricitinib, an oral drug, can reduce skin hardening in people with systemic sclerosis, a rare autoimmune disease. About 60 adults with early diffuse systemic sclerosis will receive either baricitinib or a placebo for 24 weeks. The main goal is to measure…

This study tests a combination of chemotherapy infused directly into the liver artery plus two oral drugs (lenvatinib and cadonilimab) in 42 adults with liver cancer that cannot be removed surgically. The goal is to shrink tumors enough so that patients can then receive curative …

This study tests a new, less invasive procedure to remove gallstones while keeping the gallbladder. It uses a special scope and a small mesh tube to drain the gallbladder and remove stones. The study will include 60 adults with gallstones and will check if the procedure works wel…

This study looks at how well the drug tofacitinib works for people with Blau syndrome, a rare genetic disease that causes joint, eye, and skin problems. Researchers will review medical records of 24 patients to see who responds best and why. The goal is to better control the dise…

This early study tests a new treatment called KSD-101 in 9 people with blood cancers linked to the Epstein-Barr virus. The main goal is to see if the treatment is safe and to find the best dose. Participants have cancers that did not respond to standard treatments. The study will…

This study tests whether the drug venlafaxine can reduce how often and how severe tension-type headaches are in people who get them frequently. About 432 adults aged 18-65 with 6-14 headache days per month will take the drug for 12 weeks. Researchers will track headache days and …

This study tests whether desvenlafaxine, a medication typically used for depression, can reduce how often and how severe migraines are in people who get them frequently. About 440 adults with episodic migraines will take the drug or a placebo for 12 weeks. The main goal is to see…

This study looks at whether a computer program (machine learning) can help predict if liver cancer will spread to the lungs or bones. Over 1,500 adults with liver cancer but no signs of spread at the start were followed during their regular care. The goal is to see if the tool's …

This study follows 100 children under 17 with Crohn's disease to see how the condition shows up, what treatments doctors choose, and how kids improve over time. Researchers will track symptoms and remission rates at 14 and 54 weeks. No new treatment is given—this is an observatio…