Tongji Hospital

This early-phase study tests a single injection of a gene therapy called V001-BCMA for people with autoimmune diseases like lupus that have not responded to standard treatments. The therapy targets and modifies specific immune cells to reduce disease activity. The main goal is to…

This study tests a new, less invasive way to remove gallstones using a tube placed through the stomach or intestine into the gallbladder. The goal is to clear the stones while keeping the gallbladder intact, potentially avoiding the risks of traditional surgery. Sixty adults with…

This early study tests a new treatment called KSD-101 in 9 adults with blood cancers linked to the Epstein-Barr virus. The main goal is to find a safe dose and see if it shrinks tumors. Participants must have tried standard treatments without success.

This study is looking at how well the drug tofacitinib works for people with Blau syndrome, a rare genetic condition that causes inflammation in the joints, eyes, and skin. Researchers will review medical records from 24 participants to see if tofacitinib helps control the diseas…

This phase 4 trial tests whether baricitinib, a drug already used for rheumatoid arthritis, can help people with systemic sclerosis—a rare disease that causes skin thickening and organ damage. Sixty participants will receive either baricitinib or standard treatment for 24 weeks, …

This study tests whether desvenlafaxine, a drug typically used for depression, can help prevent migraines in adults who have frequent attacks. Researchers will compare the drug to a placebo in 440 participants over 12 weeks. The goal is to see if it reduces the number of migraine…

This study tests whether the antidepressant venlafaxine can reduce how often and how severe tension-type headaches are in people who get them frequently. About 432 adults aged 18-65 with 6-14 headache days per month will take the drug for 12 weeks. Researchers will track headache…

This study is testing a machine learning tool that predicts the risk of liver cancer spreading to the lungs or bones. Over 1,500 adults with liver cancer but no signs of spread are being followed to see if the tool helps doctors make better decisions about monitoring. The tool gi…

This study compares two surgical techniques—laparoscopic (keyhole) and open surgery—for treating a rare cancer near the pancreas called nonpancreatic periampullary adenocarcinoma. Researchers will track how long patients stay in the hospital after surgery, as well as survival rat…

This study follows 100 children with Crohn's disease to track their symptoms, treatments, and outcomes in everyday medical care. Researchers will look at how different therapies—like special diets, medications, or fecal transplants—affect disease activity over 14 to 54 weeks. The…