New pain drug could make day surgery safer and faster
NCT ID NCT07409311
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study looks at whether a drug called osellidine can provide good pain relief during hysteroscopic surgery with fewer side effects than traditional opioids. It will involve 310 adults having day surgery. The goal is to see if osellidine leads to fewer breathing problems, less nausea, and quicker recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Osellidine (a painkiller)
- What this could lead to
- If it works, osellidine could offer a safer pain relief option for day surgeries, with fewer side effects and faster recovery.
- What could go wrong
- This is an early feasibility study, not yet recruiting. Results may not apply to all patients, and osellidine's effectiveness compared to standard opioids is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 310 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult female patients (age \>18 years) scheduled for gynecological hysteroscopic surgery under LMA general anesthesia at a single center.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \> 18 years. * Scheduled to undergo gynecological hysteroscopic surgery under general anesthesia with laryngeal mask airway (LMA). * Willing and able to provide written informed consent. Exclusion Criteria: * Incomplete medical records or data. * Severe hepatic or renal dysfunction. * Concurrent use of other potent analgesics (e.g., opioids, NSAIDs) or medications that may interfere with study outcomes. * Participation in another clinical trial within the past 4 weeks
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.