Sun Yat-sen University
Clinical trials sponsored by Sun Yat-sen University, explained in plain language.
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Drug combo paves way for Kidney-Saving surgery in tough cancer cases
Disease control CompletedThis study tested whether giving a combination of two drugs (cadonilimab and lenvatinib) before surgery could help patients with high-risk kidney cancer successfully undergo a kidney-sparing operation. The goal was to shrink tumors enough to make a complex, kidney-preserving surg…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Apr 03, 2026 21:41 UTC
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New drug combo tested for Tough-to-Treat ovarian cancer
Disease control CompletedThis study tested whether adding a new drug called apatinib to a standard chemotherapy (etoposide) could help control advanced ovarian cancer that had stopped responding to platinum-based treatments. It involved 35 women to see if the combination was effective and safe. The goal …
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Apr 03, 2026 21:41 UTC
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Could a common antibiotic help stop breast cancer from coming back?
Disease control CompletedThis large, completed study tested whether adding the antibiotic moxifloxacin to standard chemotherapy after breast cancer surgery helps keep the cancer from returning. It involved 559 patients who had surgery for operable breast cancer. The goal was to see if this combination im…
Phase: PHASE3 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Apr 03, 2026 21:40 UTC
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Real-World look at aggressive liver cancer treatment
Disease control CompletedThis study looked back at medical records to see how well a combination treatment worked for people with advanced liver cancer. The treatment combined two immunotherapy drugs with a special type of chemotherapy delivered directly to the liver. Researchers analyzed data from about…
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Can a short insulin pump 'Reset' help newly diagnosed diabetes?
Disease control CompletedThis study tested if using a short-term insulin pump along with different oral diabetes pills could lead to better long-term blood sugar control in people newly diagnosed with type 2 diabetes. It involved 264 participants who had not yet taken any diabetes or cholesterol medicati…
Phase: PHASE4 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Liver cancer breakthrough: skip surgery when tumors vanish?
Disease control CompletedThis study aimed to find out if liver cancer patients still need surgery after their tumors disappear following initial drug and artery-based treatments. Researchers randomly assigned 74 patients whose tumors had vanished to either have surgery or be closely monitored without sur…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New attack on tough liver cancer: testing a Double-Dose chemo strategy
Disease control CompletedThis study tested if adding a direct liver chemotherapy infusion to a standard three-part treatment helps people with advanced bile duct cancer. It involved 96 patients whose cancer could not be removed by surgery. The goal was to see if this more intensive approach could help pa…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New combo attack on tough liver cancer shows promise
Disease control CompletedThis study tested a new combination treatment for people with advanced liver cancer that had spread into a major vein in the liver. Researchers combined a targeted chemotherapy delivered directly to the liver with an immunotherapy drug designed to help the immune system fight can…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New hope for women with returning cervical cancer
Disease control CompletedThis study tested a new treatment combination for women whose cervical cancer has returned after standard chemotherapy. It combined an immunotherapy drug (anti-PD-1) with a chemotherapy drug (albumin-bound paclitaxel) to see if it could shrink tumors and control the disease. The …
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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AI steps in to guide doctors in liver cancer battle
Disease control CompletedThis study tested a new artificial intelligence (AI) tool designed to help doctors make better treatment decisions for patients with liver cancer (hepatocellular carcinoma). The AI analyzed patient data to predict how the disease might progress and how well different treatments l…
Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Testing easier dosing to keep advanced colon cancer in check
Disease control CompletedThis study tested whether giving two cancer drugs (cetuximab and capecitabine) less often could safely help control advanced colorectal cancer that had responded to initial treatment. It involved 24 adults with a specific genetic type of cancer that had spread. The main goals wer…
Phase: PHASE1, PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated Feb 27, 2026 15:18 UTC
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New scan combo aims to spot hidden cancer spread
Diagnosis CompletedThis study aimed to find a better way to diagnose whether small lymph nodes in the neck contain cancer that has spread from nasopharyngeal carcinoma (a type of head and neck cancer). Researchers tested a combination of MRI scans and a special contrast-enhanced ultrasound on 348 p…
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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New scan could help rectal cancer patients avoid surgery
Diagnosis CompletedThis study tested whether a new type of PET scan (using a tracer called 18F-FAPI) can accurately predict which patients with rectal cancer will have a complete response to their pre-surgery treatment. The goal is to better identify patients who might be able to avoid major surger…
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Diagnosis
Last updated Mar 20, 2026 14:47 UTC
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New hope for chemo patients: drug trial aims to stop numbness and pain
Symptom relief CompletedThis study tested whether a drug called Neurotropin can prevent or reduce nerve damage (neuropathy) caused by a common chemotherapy drug, oxaliplatin, in people with stage II or III colorectal cancer. Over 300 patients were randomly assigned to receive either Neurotropin or a pla…
Phase: PHASE3 • Sponsor: Sun Yat-sen University • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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Can a fancy electric toothbrush really give you a whiter smile?
Symptom relief CompletedThis study aimed to see if two specific models of Oclean sonic electric toothbrushes were better at reducing surface tooth stains than a standard Oral-B manual toothbrush. Over 8 weeks, 129 adults with noticeable tooth staining used one of the assigned brushes. Researchers measur…
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Symptom relief
Last updated Mar 27, 2026 12:38 UTC
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Better pain relief after lung surgery? study tests new delivery method
Symptom relief CompletedThis study tested two different ways of delivering pain medication through an epidural after lung surgery. Researchers wanted to see if giving the medicine in scheduled, larger doses (PIEB) was better for recovery than the standard method of a slow, continuous drip (CEI). They me…
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Symptom relief
Last updated Mar 23, 2026 15:15 UTC
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Scientists analyze breast milk to close nutrition gap for premature babies
Knowledge-focused CompletedThis study reviewed existing research to compare the nutrient content of breast milk from mothers who delivered preterm versus full-term babies. The goal is to better understand the nutritional differences to help improve feeding strategies for vulnerable premature infants. Resea…
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Low oxygen after surgery linked to dangerous leaks, study finds
Knowledge-focused CompletedThis study looked back at past patients to see if low oxygen levels after esophageal cancer surgery are linked to a higher chance of the surgical connection leaking. Researchers reviewed the records of over 2000 patients who had this surgery, comparing those with low oxygen to th…
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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A phase 3 randomized controlled study of metronomic capecitabine combined with aromatase inhibitor versus aromatase inhibitor alone for first line treatment in hormone receptor-positive, Her2-negative metastatic breast cancer
CompletedThe study is designed to compare the clinical benefit following treatment with aromatase inhibitor in combination with metronomic capecitabine versus aromatase inhibitor alone in women with hormone receptor-positive, Her2-negative advanced breast cancer who have not received prio…
Phase: PHASE3 • Sponsor: Sun Yat-sen University
Last updated Mar 02, 2026 15:25 UTC