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New drug cocktail shows promise for rare sarcomas

NCT ID NCT04172805

First seen Jun 17, 2026 · Last updated Jun 23, 2026 · Updated 2 times

Summary

This phase 2 trial tested a combination of two drugs—anlotinib and toripalimab—in 70 people with advanced soft-tissue sarcoma that had stopped responding to standard treatment. The goal was to see if the combo could shrink tumors or slow the disease. The study is now complete.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Xing Zhang

    Guangzhou, Guangdong, 510060, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anlotinib and toripalimab

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced soft-tissue sarcoma who have run out of standard therapies.

What could go wrong

This is a small, early-phase trial with no control group, so results may not be definitive. Side effects from the drug combination could be serious.

Conditions

The condition(s) this trial relates to.

sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.