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New combo therapy may help newly diagnosed diabetics go Drug-Free for a year

NCT ID NCT01471808

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 35 times

Summary

This study tested whether adding oral diabetes drugs (metformin/pioglitazone or sitagliptin) to a short-term insulin pump can improve long-term blood sugar control and help newly diagnosed type 2 diabetes patients achieve remission. 264 participants who were newly diagnosed, not on any diabetes medication, and had moderate to high blood sugar were enrolled. The main goal was to see how many could maintain normal blood sugar without medication for one year after the short intensive treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.