Sun Yat-sen University

This study is testing whether adding a drug called apatinib to a standard treatment plan helps people with advanced esophageal cancer that cannot be removed by surgery. The standard plan involves chemotherapy, immunotherapy, and radiation. Researchers will compare the outcomes of…

This study is testing a treatment approach for muscle-invasive bladder cancer that aims to avoid removing the bladder through major surgery. Participants receive a combination of chemotherapy, immunotherapy (toripalimab), and radiation therapy. The goal is to see if this non-surg…

This study is testing whether adding a new immunotherapy drug called cadonilimab to standard chemotherapy and radiation can better control cancer and prevent it from returning in patients with locally advanced esophageal cancer that cannot be removed by surgery. The trial will en…

This study is testing a new three-drug combination as the first treatment for people whose nasopharyngeal cancer (a type of head and neck cancer) has returned or spread. The treatment involves two targeted drugs and a chemotherapy pill, given for 4-6 cycles, followed by ongoing m…

This large Phase 3 trial is testing whether doctors can safely reduce the size of the radiation treatment area for patients with advanced nasopharyngeal (upper throat) cancer. The study compares targeting the original tumor size versus the smaller size after initial chemotherapy,…

This study compares two approaches for men whose prostate cancer has spread to nearby lymph nodes after surgery. Researchers want to see if adding pelvic radiation to standard hormone therapy helps keep the cancer from returning longer than hormone therapy alone. About 374 partic…

This study is testing whether a combination of two drugs can help prevent a less common type of kidney cancer from returning after surgery. The treatment involves an IV medication and a daily pill given for up to one year to 40 patients at high risk of their cancer coming back. T…

This study is testing whether a new combination of two drugs, cadonilimab and lenvatinib, can help control advanced endometrial cancer that has continued to grow after standard chemotherapy. It will involve about 32 patients to see how well the combination shrinks tumors and how …

This study is testing whether closing the pelvic lining during minimally invasive rectal cancer surgery helps prevent bowel paralysis after the operation. Researchers are comparing two approaches—closing the lining versus leaving it open—in 516 patients across multiple hospitals.…

This study compares two treatment approaches for advanced liver cancer that has spread into a major vein. Researchers want to see if adding a specialized liver chemotherapy to a two-drug immunotherapy and targeted therapy combination helps patients live longer. The trial involves…

This study is testing if adding a drug called thymosin alpha 1 helps people with a specific type of advanced lung cancer complete a full year of follow-up immunotherapy. The immunotherapy is given after initial chemotherapy and radiation. Researchers will compare two groups of pa…

This study is testing a combination of two immunotherapy drugs with two chemotherapy drugs as a treatment given before surgery for locally advanced esophageal cancer. The goal is to see if this 'neoadjuvant' approach can shrink or even eliminate the tumor, making surgery more eff…

This study is testing whether using medication to lower pressure inside the eye can slow down the progression of severe, worsening nearsightedness in adults. Researchers want to see if this treatment can stop the eyeball from getting longer, which is the main cause of vision prob…

This study is testing if adding a new drug called anlotinib to the standard first treatment (the Stupp regimen) helps people with newly diagnosed glioblastoma live longer without their cancer getting worse. It's a Phase 2 trial involving 150 adults, where participants are randoml…

This trial is testing a combination of two approved drugs (toripalimab and bevacizumab) with three different procedures that deliver treatment directly into the liver's arteries. The goal is to see which combined approach works best to shrink tumors and control advanced liver can…

This study is testing whether a combination of two drugs, zimberelimab and lenvatinib, can help control advanced cervical cancer that has continued to grow despite prior immunotherapy. It aims to see if this combination is safe and effective for up to 30 women whose cancer has pr…

This study is testing a new combination of three drugs as a first treatment for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination is safe and can shrink tumors or slow their growth. It will involve about 32 patients w…

This study is testing whether adding the immunotherapy drug Sintilimab to a standard chemotherapy regimen is safe and effective for people newly diagnosed with an advanced form of a rare and aggressive blood cancer called NK/T-cell lymphoma. The trial will enroll 34 adults to see…

This study is testing a three-part treatment for nasopharyngeal cancer that has spread to a few other areas in the body. It combines a type of immunotherapy (PD-1 antibody), chemotherapy, and very precise, high-dose radiation (SBRT). The goal is to see if this combination can bet…

This study is testing a new ultrasound-based scoring system to better predict which people with plaque buildup in their neck arteries are most likely to have a stroke or heart attack. Researchers will look back at past patient data and also follow new patients to see if this meth…

This study is testing if a small dose of morphine injected into the spine before surgery can better control pain and improve recovery for patients having laparoscopic colon cancer surgery. It will compare this method against standard pain management in 252 patients. The main goal…

This study observes how heart function changes in lung cancer patients receiving combined chemotherapy, radiation, and immunotherapy. Researchers measure heart performance during walking tests to see if these measurements can predict treatment side effects and survival outcomes. …