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Could less radiation be just as good for nasopharyngeal cancer?

NCT ID NCT07201337

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 40 times

Summary

This phase 3 trial is testing whether giving a lower dose of radiation to low-risk areas around the main tumor works as well as the standard higher dose for nasopharyngeal cancer. The study plans to enroll 700 people aged 18-70 with newly diagnosed, non-spreading cancer. The goal is to see if the reduced dose can control the cancer just as well while causing fewer side effects and improving quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Affiliated Hospital of Guangdong Medical University

    RECRUITING

    Zhanjiang, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center

    RECRUITING

    Shenzhen, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dongguan People's Hospital

    RECRUITING

    Dongguan, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun yat-sen university cancer center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The University of Hong Kong-Shenzhen Hospital

    RECRUITING

    Shenzhen, Guangdong, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If successful, this could allow doctors to use lower radiation doses for some patients, reducing long-term side effects while still controlling the cancer.

What could go wrong

This is a large phase 3 trial, but it's testing a non-inferiority approach—meaning the reduced dose might not be as effective as the standard. Results may not apply to all patients.

Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.