Could less radiation be just as good for nasopharyngeal cancer?

NCT ID NCT07201337

Recruiting now Disease control Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial is testing whether giving a lower dose of radiation to low-risk areas around the main tumor works as well as the standard higher dose for nasopharyngeal cancer. The study plans to enroll 700 people aged 18-70 with newly diagnosed, non-spreading cancer. The goal is to see if the reduced dose can control the cancer just as well while causing fewer side effects and improving quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: radiation therapy
What this could lead to: If successful, this could allow doctors to use lower radiation doses for some patients, reducing long-term side effects while still controlling the cancer.
What could go wrong: This is a large phase 3 trial, but it's testing a non-inferiority approach—meaning the reduced dose might not be as effective as the standard. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASOPHARYNGEAL CANCINOMA (NPC)

Contacts and locations

Locations

Affiliated Cancer Hospital of Shantou University Medical College
RECRUITING

Shantou, Guangdong, China
Affiliated Hospital of Guangdong Medical University
RECRUITING

Zhanjiang, Guangdong, China
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
RECRUITING

Shenzhen, Guangdong, China
Dongguan People's Hospital
RECRUITING

Dongguan, Guangdong, China
Sun yat-sen university cancer center
RECRUITING

Guangzhou, Guangdong, 510060, China
The University of Hong Kong-Shenzhen Hospital
RECRUITING

Shenzhen, Guangdong, China

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