Could a baking soda rinse tame radiation mouth sores?

NCT ID NCT06854510

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study tests whether gargling with a 2.5% sodium bicarbonate (baking soda) solution during radiation therapy can reduce the severity of painful mouth sores in people with nasopharyngeal carcinoma. Participants will rinse with the solution several times a day throughout their radiation course. The goal is to see if this simple, low-cost approach improves comfort and helps patients complete their cancer treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a 2.5% sodium bicarbonate mouthwash
What this could lead to
If effective, this cheap and easy mouthwash could become a standard way to prevent severe mouth sores during radiation therapy for nasopharyngeal cancer.
What could go wrong
This is a single-center study with 196 participants, so results may not apply to all patients. The mouthwash may not reduce severe mucositis as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

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