Spinal morphine may ease pain and speed recovery after colon cancer surgery
NCT ID NCT06636864
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether giving morphine into the spine (intrathecal) before laparoscopic colon cancer surgery helps patients feel better and recover faster. About 252 adults having this surgery will be invited to join. The goal is to see if this approach reduces pain, cuts down on other painkillers, and improves overall recovery quality.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 252 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Oct 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Laparoscopic colorectal cancer surgery under tracheal intubation and general anesthesia is intended * Agreed to use intravaginal morphine injection and bupivacaine liposomal plane block of transversal muscle after surgery * ASA Grade I - III * Over 18 years of age Exclusion Criteria: * Preoperative accident or subjective refusal of surgery * Nervous system dysfunction * Contraindications to intraspinal anesthesia * Preoperative opioid use history * Patients with abnormal preoperative pain and pain score (NRS) \>3
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sun Yat-Sen University Cancer Center
Guangzhou, Guangdong, China
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Other studies related to the condition(s) this trial covers.
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- Missed Follow-Up colonoscopies: do they raise the risk of advanced growths?
- A 2.2 mm scope could spot cancerous tissue in minutes, not days