London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

This study tested giving focused radiation before breast cancer surgery instead of the usual 5-6 weeks after surgery. 139 women with early-stage breast cancer received either one or three doses of radiation before their lumpectomy. The goal was to see if this approach can prevent…

This study tested a new radiation technique called SABR in 13 adults with cancer that had spread to more than 10 spots in the body. The goal was to see if giving high-dose, precise radiation to all cancer sites is safe. Researchers looked for side effects and quality of life chan…

This large registry study is testing whether a special type of PET scan, called PSMA-PET, can better detect where prostate cancer has returned after initial treatment. Thousands of men with suspected recurrent prostate cancer across Ontario will receive this scan. The goal is to …

Electromyography (EMG) and nerve conduction studies (NCS) check how nerves and muscles work, and many patients find them painful or stressful. Researchers are testing whether letting adults choose and listen to their own music during these tests lowers anxiety and pain compared w…

This study tested whether virtual reality (VR) can reduce pain and distress in children with cancer when they get a needle put into their port-a-cath. 84 children aged 5 to 17 were randomly assigned to use VR, an iPad, or no special distraction during the procedure. Researchers m…

Some people develop an irregular heartbeat called atrial fibrillation after a stroke or mini-stroke. Researchers want to understand what causes this by comparing nerve function, inflammation, and heart rate patterns in three groups: patients with this post-stroke irregular heartb…

This study looks at why people on dialysis for kidney failure often have dangerous heart rhythms. Researchers implanted a small heart monitor in 18 patients to track their heartbeats for up to three years. They also used CT scans and ultrasound to see if the dialysis procedure it…

This study examined over 31,000 older adults (65+) with chronic kidney disease to see if starting a higher dose of the sleep medication trazodone (75-150 mg/day) leads to more serious events like hospital visits or death within 30 days compared to a lower dose (25-75 mg/day). The…

This completed study compared nearly 10,000 male living kidney donors to similar non-donors to see if laparoscopic nephrectomy increases the long-term chance of needing scrotal surgery, such as for fluid collections. Researchers used health databases in Ontario, Canada, tracking …

This study tested whether taking the drug BYL719 (Alpelisib) for 14 days before surgery could change certain biological markers in head and neck cancer tissue. Fifteen patients with resectable head and neck squamous cell cancer took the drug, and researchers compared tissue sampl…