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Higher antidepressant dose may be risky for seniors with kidney issues

NCT ID NCT07399795

First seen Feb 16, 2026 · Last updated May 17, 2026 · Updated 9 times

Summary

This study examined the safety of starting citalopram at 20 mg/day versus 10 mg/day in adults aged 65 and older with reduced kidney function. Researchers analyzed health records from over 7,000 participants to see if the higher dose increased the risk of hospitalization, emergency visits, or death within 30 days. The goal was to gather knowledge on medication risks, not to provide treatment.

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Contacts and locations

Locations

  • London Health Sciences Centre Research Institute

    London, Ontario, Canada

Conditions

Explore the condition pages connected to this study.