Higher antidepressant dose may pose risks for seniors with weak kidneys
NCT ID NCT07399795
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at over 7,000 older adults (65+) with reduced kidney function who started taking the antidepressant citalopram. Researchers compared a 20 mg/day dose to a 10 mg/day dose to see if the higher dose increased the risk of serious events like hospitalization, emergency visits, or death within 30 days. The goal was to provide safety information to guide prescribing in this vulnerable group.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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London Health Sciences Centre Research Institute
London, Ontario, Canada
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