Higher antidepressant dose may pose risks for seniors with weak kidneys
NCT ID NCT07399795
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at over 7,000 older adults (65+) with reduced kidney function who started taking the antidepressant citalopram. Researchers compared a 20 mg/day dose to a 10 mg/day dose to see if the higher dose increased the risk of serious events like hospitalization, emergency visits, or death within 30 days. The goal was to provide safety information to guide prescribing in this vulnerable group.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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London Health Sciences Centre Research Institute
London, Ontario, Canada