ELDERLY

This study compares two seasonal flu vaccines—one with an extra ingredient to boost the immune response (adjuvanted) and one without—in 200 adults aged 65 and older who have chronic health issues like heart disease or diabetes. The goal is to see which vaccine triggers a stronger…

This study looks at whether metformin, a common diabetes medicine, can improve mild memory problems in older adults who are overweight or obese. About 54 people aged 60-75 will take metformin or a placebo for 26 weeks, along with lifestyle advice. The goal is to see if metformin …

This study tests whether giving elderly patients with kidney disease a personalized amount of fluids, guided by a lung water monitor, can prevent acute kidney injury after coronary angiography. About 320 participants aged 60 and older will receive either tailored hydration or sta…

This early-stage study tests whether a combination of two experimental drugs, GI-102 and GIB-7, can improve immune function and other signs of aging in healthy adults and cancer survivors. The trial involves 15 participants and lasts 8 weeks, focusing on safety and changes in imm…

This study looks at two ways to treat a specific type of neck fracture (odontoid fracture) in people aged 70 and older. Participants will be randomly assigned to either surgery or wearing a rigid neck collar. The goal is to see which treatment helps them recover better in daily a…

This study tests a chatbot that guides people through telling their life stories, with help from a trained facilitator. The goal is to see if this process improves emotional well-being, identity, and recovery. The study includes healthy adults, adults with mental health condition…

This study looks at whether adding local muscle vibration to standard rehabilitation can help elderly patients (75+) recover muscle strength and mobility after hip fracture surgery. About 25 participants will receive vibration sessions five times a week for four weeks. The main g…

This study looks at whether using a positive airway pressure (PAP) machine at night can improve thinking, sleepiness, and quality of life in older veterans (age 60+) who have both COPD and obstructive sleep apnea (called overlap syndrome). About 668 veterans will be followed to s…

This study looks at people over 60 who had a stroke linked to a common heart hole called PFO. It compares three treatments: closing the hole, taking blood thinners, or using antiplatelet drugs. The goal is to see which option best prevents another stroke. About 400 older adults w…

This study looks at whether stopping antibiotics early is safe for people 65 and older who are in the hospital for a viral lung infection. Many older patients get antibiotics even when they don't have a bacterial infection, which can cause side effects. The researchers will compa…

This study looks at whether simple blood tests and brain scans can help predict which older adults with memory loss and frailty will need to visit the emergency room within six months. Researchers will follow 110 participants aged 65 and older who have lost some independence. The…

This study explores whether singing—alone or in a group—is a practical activity for older adults with coronary artery disease. Researchers will measure how many people join and stick with the program. The goal is to see if singing can become a regular habit to improve heart healt…

This study is testing whether a team of doctors from different specialties can create better treatment plans for older adults (ages 60-90) with lung cancer. Each patient will get a personalized plan based on a full health assessment. The goal is to see if this approach improves h…

This study is watching 1,200 older adults (65+) before, during, and after surgery to learn why some get complications like confusion (delirium). Researchers will collect blood samples and health information to build a tool that predicts these risks. The goal is to better understa…

This study looks at how well the body uses protein from peas in healthy young and older adults who are either vegetarian or eat meat. Researchers want to see if age or diet changes how plant proteins are digested. The results will help create better nutrition advice for older peo…

This study looks at whether elderly men (70+) with prostate cancer who have been on hormone therapy for over 3 years can safely stop it. Researchers will check if their testosterone stays at castrate levels without ongoing treatment. The goal is to see if stopping is feasible and…

This study looks at why older adults (60+) respond differently to exercise. Researchers will measure muscle power and blood markers in 900 participants to understand why some improve more than others. The goal is to create personalized physical activity plans that work better for…