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Antidepressant doses under scrutiny for kidney patients

NCT ID NCT07531173

First seen Apr 26, 2026 · Last updated May 23, 2026 · Updated 2 times

Summary

This study examined whether starting a higher dose of two common antidepressants (venlafaxine or duloxetine) increases the risk of serious events like emergency visits, hospital stays, or death within 30 days in older adults (66+) with chronic kidney disease. Researchers analyzed data from over 8,600 patients who were not on dialysis or had a kidney transplant. The goal was to understand if higher doses pose extra danger for this group.

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