London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's

This trial is testing whether using highly focused, high-dose radiation on a few spots where cancer has started to spread can help delay the disease from getting worse. It compares this approach to continuing standard drug treatments alone in patients whose cancer was previously …

This study is testing if giving a short, targeted course of radiation before standard chemotherapy can improve treatment for people with high-risk, locally advanced breast cancer. The idea is that the radiation might 'prime' the immune system to help the chemotherapy work better.…

This study is testing a precise form of radiation therapy for people with early-stage lung cancer who also have a serious lung-scarring disease (ILD) and cannot have surgery. The goal is to see if this targeted radiation can control the cancer and extend life without causing seve…

This study aims to find the safest and most effective dose of a precise, high-dose radiation treatment called SBRT for lung tumors located near major airways and blood vessels. It will enroll 30 patients with early-stage non-small cell lung cancer to carefully test increasing rad…

This study is testing whether giving an extra, targeted dose of radiation to the most active parts of a lung tumor can improve treatment results. It compares standard chemoradiation to the same treatment with this added 'boost.' The main goal is to see if this approach reduces th…

This study aimed to compare a less invasive needle procedure (VAPE) to standard surgery for completely removing non-cancerous but high-risk breast growths. It planned to see if the needle method was as effective, safer, and led to better cosmetic results and patient satisfaction.…

This small, early-stage study is testing if adding a short, second type of dialysis between a patient's regular sessions can better control dangerous fluid and salt buildup. Ten patients on standard hemodialysis will have a temporary tube placed to receive this extra fluid-removi…

This study is comparing two standard treatments for early-stage throat cancer caused by HPV: surgery and radiation therapy. The goal is to see which approach gives patients the best chance of survival while also preserving their quality of life, like swallowing and speaking. It w…

This study is testing if a fecal transplant (transferring healthy gut bacteria from a donor) can help patients with advanced kidney cancer better tolerate a powerful two-drug immunotherapy combination. The goal is to reduce severe side effects so patients can stay on their cancer…

This study aimed to see if the drug hydroxychloroquine could prevent COVID-19 in older, high-risk adults living in care facilities after they were exposed to the virus. It was designed as a Phase 3 trial but was withdrawn before any participants were enrolled. The goal was to giv…

This study is testing whether a new type of talk therapy called Deep Brain Reorienting (DBR) can help reduce symptoms of Post-Traumatic Stress Disorder (PTSD). About 234 adults with PTSD will either receive the DBR therapy right away or be placed on a waitlist. The therapy involv…

This study is testing a new group therapy program designed to reduce loneliness in older adults who are patients in a psychiatric hospital. The program, called 'Awareness, Courage, and Love Groups,' aims to help participants feel more socially connected. Researchers are checking …

This study is testing a special group therapy program designed to help older adults with mental health conditions feel less lonely. The program, called Awareness, Courage, and Love (ACL) Groups, involves eight sessions. Researchers want to see if this type of group is practical t…

This study aims to develop a test to predict which breast cancer patients might experience severe side effects or poor response to a common class of drugs called CDK4/6 inhibitors. Researchers will analyze blood samples and genetic information from 100 female patients taking thes…