Centre For Addiction And Mental Health

This study tested a 4-week virtual program for people with moderate to severe alcohol use disorder. The program included group therapy and daily breathalyzer checks, all done from home. Researchers wanted to see if people would stay in the program and if they were satisfied with …

This study tested a healthbot (a conversational computer program) designed to help people stick with their varenicline medication, which is used to quit smoking. Researchers worked with 40 smokers in Ontario who were ready to quit. The goal was to see if the healthbot was easy to…

This study looked at whether a version of cognitive behavioural therapy (CBT) adapted for South Asian culture could help reduce depression and anxiety. Researchers worked with 146 Canadian adults of South Asian origin who had mild to severe symptoms. The therapy was taught to the…

This study tested whether adding the antibiotic minocycline to usual treatment can reduce depressive symptoms in adults with treatment-resistant depression. About 76 participants took either minocycline or a placebo for 12 weeks. The goal was to see if the drug, which reduces bra…

This study tested whether people going through alcohol withdrawal can be safely treated at home using telemedicine instead of going to the hospital. 30 adults who wanted to quit drinking received remote care over 3 days. The goal was to see if this approach keeps people in treatm…

This study looked at whether an online cognitive behavioral therapy program, called Breaking Free Online, helps people reduce their substance use. 198 adults with substance use disorder were split into three groups: standard care with group peer support, the online program alone,…

This study tested whether cytisine, a plant-based medication, is safe and helpful for quitting smoking in people who also have alcohol use disorder. Twenty adults who smoked daily and wanted to quit took cytisine for a short time. Researchers tracked side effects and how many peo…

This study tested a new group therapy program for depressed parents of children aged 6 to 10 with emotional or behavioral issues. The goal was to see if the program was practical and liked by parents. About 80 parents took part to help improve future treatments.

This study compares a 6-month version of dialectical behaviour therapy (DBT) to the standard 1-year program for people with borderline personality disorder who repeatedly self-harm. Researchers want to see if the shorter treatment is just as good at reducing self-harm and is more…

This study tested a culturally adapted version of cognitive behavioral therapy (CA-CBT) for Chinese youth aged 12 to 21 in Ontario who have anxiety or depression. The goal was to see if making therapy more culturally relevant improves access and mental health outcomes. Researcher…

This study tested whether sending text message reminders to young people (ages 14-35) who had a first episode of psychosis could help them attend their first appointment at an early psychosis program after being seen in the emergency department. The study involved 186 participant…

This study tested two different ways of using magnetic pulses on the scalp to see which one better improves the brain's ability to change and adapt (plasticity). 29 healthy, right-handed adults aged 18-50 took part. Researchers compared a standard method used for depression with …

This study looked at whether brain insulin resistance plays a role in depression during adolescence. Researchers used MRI scans to compare brain activity in teens with and without depression after giving them insulin or a placebo through the nose. The goal was to better understan…

This study tested a mobile app called App for Independence-O (A4i-O) designed to support people with opioid use disorder. Fourteen adults used the app for one month while in outpatient treatment. The goal was to see if the app works well and is easy to use, not to measure health …

This study looked at whether a new social-emotional learning program called EMPOWER can be used in after-school programs for youth aged 11-14. Researchers wanted to see if the program is practical and liked by staff and kids, and if it helps improve emotional skills, resilience, …

This study followed 51 people with schizophrenia who were already stable on long-acting injectable antipsychotics. Over 48 weeks, researchers checked if symptoms returned when patients reliably received their medication. The goal was to see how often relapse happens when adherenc…

This study tested whether a special anti-stigma program helps healthcare workers treat people with mental health or substance use problems more fairly. About 485 staff and clients from six health centers took part, with three centers getting the program and three not. Surveys mea…

This study tested a program called HOP-C that provides team-based support—including case management, peer support, and mental health help—to youth aged 16-25 who recently moved into stable housing after being homeless. The goal was to see if this extra support helps them stay hou…

This study looked at how a noninvasive brain stimulation technique called TMS changes the way people with body dysmorphic disorder (BDD) see faces. Forty adults with BDD or mild symptoms received TMS and then had their brains scanned while looking at pictures of their own face. T…

This study looked at 600 children with disruptive behavior disorders like ADHD and oppositional defiant disorder. Researchers created personal profiles based on the child's emotions, thinking, and family factors to see if they could predict which kids would benefit most from ther…

This study tested whether a new social-emotional learning curriculum could be successfully added to a STEM after-school program for youth aged 11 to 14. Researchers worked with 26 participants, including students, staff, and parents, to see if the program was practical and well-l…

This study looked at how nabilone, a cannabis-like drug, changes a brain enzyme called FAAH in 10 healthy adults. Participants took nabilone for one week and had brain scans before and after. The goal was to understand how the drug works in the brain, not to treat any disease.

This study looked at whether psilocybin (the active ingredient in magic mushrooms) needs to cause psychedelic effects to help with depression. 41 adults with treatment-resistant depression were given either psilocybin alone, psilocybin plus risperidone (a drug that blocks the psy…

This study looked at whether a program called NAVIGATE helps youth (ages 14-35) having their first episode of psychosis get better coordinated care. Researchers worked with 100 participants across Ontario to see if the program reduces hospital stays and ER visits. The goal was to…