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Chatbot could help smokers stay on track with quit meds

NCT ID NCT05997901

Symptom relief Sponsor: Centre for Addiction and Mental Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a healthbot—a conversational computer program—designed to help people remember to take their varenicline (a prescription medication to help quit smoking). Researchers worked with 40 smokers in Ontario who were starting varenicline. Participants used the healthbot for 12 weeks, and the team measured how acceptable, useful, and easy to use the bot was, as well as whether it improved medication adherence and smoking cessation.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
healthbot (conversational agent)
What this could lead to
If it works, this could lead to a simple, supportive tool that helps people stay on track with their smoking cessation medication, potentially improving quit rates.
What could go wrong
This is a small, early feasibility study with only 40 participants. It focuses on whether the healthbot is acceptable and usable, not on proving it helps people quit. The results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

Jun 2024

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Treatment-seeking smokers who are willing to start taking varenicline and continue it for 12 weeks, and set a quit date in the next 30 days; * Smoke cigarettes daily (10 or more cigarettes a day) * Age ≥ 18 years; * Speak/read English; * Have a smartphone with data plan; * Report being committed to answering questions during follow-up; * Live in Ontario. Exclusion Criteria: * Have contraindication(s) to varenicline use; * Are pregnant/planning to become pregnant/breastfeeding; * Participated in the co-design phase.

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Conditions

The condition(s) this trial relates to.

Medication Adherence Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Medication adherence Smoking cessation

Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    Toronto, Ontario, M6J1H4, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.