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Teen depression: is the brain ignoring insulin?

NCT ID NCT05571878

First seen Mar 31, 2026 · Last updated May 23, 2026 · Updated 10 times

Summary

This study looked at whether brain insulin resistance plays a role in depression during adolescence. Researchers used MRI scans to compare brain activity in teens with and without depression after giving them insulin or a placebo through the nose. The goal was to better understand the biology of depression, not to test a treatment.

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Contacts and locations

Locations

  • Centre for Addiction and Mental Health

    Toronto, Ontario, M6J 1H3, Canada

Conditions

Explore the condition pages connected to this study.