Al-azhar University
Clinical trials sponsored by Al-azhar University, explained in plain language.
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Tiny bone holes may help adults get a wider smile without surgery
Disease control CompletedThis study tested a dental device called a hybrid rapid maxillary expander, sometimes combined with tiny bone perforations (MOPs), to widen the upper jaw in adults aged 17-23. Fourteen people with a narrow upper jaw and crossbite took part. The goal was to see if the bone holes h…
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 24, 2026 02:33 UTC
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Hip fracture showdown: full vs. partial replacement in seniors
Disease control CompletedThis completed trial compared two types of hip surgery—total hip replacement and partial hip replacement—in 40 active elderly patients (65+) who had a displaced hip fracture. The goal was to see which surgery leads to better function and recovery. Results could help surgeons choo…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 23, 2026 11:58 UTC
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Flexible dentures may beat rigid ones for implant fit
Disease control CompletedThis study tested two types of denture material for people with no teeth who got implant-supported overdentures. Sixteen patients received either a standard acrylic denture or a flexible resin one. Researchers measured gum pocket depth, plaque buildup, and Candida yeast growth to…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 23, 2026 11:56 UTC
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Could a tree extract beat bad breath in kids with braces?
Disease control CompletedThis study tested whether a mouthwash made from Moringa extract can reduce bacteria in the mouths of children aged 8 to 12 who wear removable braces. Sixty children were split into two groups: one used the Moringa mouthwash daily, the other followed standard oral hygiene. Researc…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 23, 2026 11:55 UTC
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Natural compound boosts dental implant success in small trial
Disease control CompletedThis study tested a gel made from kaempferol, a natural plant compound, placed at the implant site during dental implant surgery in 30 patients. The kaempferol group showed higher bone-building activity in the first weeks and greater bone density after 6 months compared to the co…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 22, 2026 12:07 UTC
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Dental device showdown: which expander moves molars best?
Disease control CompletedThis study tested two different dental expanders in 30 teenagers aged 15-18 who needed their upper molars moved backward to correct a Class II bite. One device was a self-activated Leaf Expander and the other a conventional Hyrax Expander, both anchored to the jawbone. The goal w…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 22, 2026 12:04 UTC
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New jaw expander could improve smiles for kids with cleft lip and palate
Disease control CompletedThis study tested a new device called the Leaf Self Expander to widen the upper jaw in 20 children with cleft lip and palate. The device was compared to the standard rapid maxillary expander. Researchers used 3D scans to measure changes in bone and tooth position. The goal was to…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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Denture showdown: which attachment keeps your jawbone healthier?
Disease control CompletedThis completed study tested two types of attachments (ball-and-socket vs Equator) for lower jaw implant-supported dentures in 24 adults aged 55-60. Researchers measured bone loss around the implants and how bite forces were distributed. The goal was to see which attachment provid…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 22, 2026 11:56 UTC
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Diabetes drug may boost dental implant success, small study finds
Disease control CompletedThis study looked at whether adding 1% metformin gel to a bone graft improves bone healing and implant stability in people getting immediate dental implants. Twenty adults aged 18 to 40 with a non-restorable tooth in the front or premolar area took part. The researchers measured …
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 18, 2026 11:47 UTC
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Liquorice gel takes on laser in gum disease showdown
Disease control CompletedThis study compared a liquorice nanogel to a diode laser as extra treatments for advanced gum disease (stage III). 27 adults with deep gum pockets received one of the two treatments alongside standard care. The goal was to see which approach better reduced harmful bacteria and im…
Phase: PHASE3 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 17, 2026 12:09 UTC
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New surgery offers hope for kids with stubborn constipation
Disease control CompletedThis study tested a two-part surgery for children with severe constipation that didn't get better with standard treatments. The surgery removes part of the colon and creates a small opening in the belly for enemas. The goal was to reduce accidental stool leakage (soiling). The st…
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 17, 2026 12:07 UTC
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Less invasive parotid tumor surgery shows promise in new trial
Disease control CompletedThis study compared two surgical methods for removing non-cancerous parotid gland tumors: a newer, less invasive technique called intracapsular parotidectomy (ICP) and the standard superficial parotidectomy (SP). Researchers wanted to see if ICP could reduce complications like fa…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 17, 2026 12:04 UTC
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PCOS fertility boost: does adding cabergoline to letrozole improve ovulation?
Disease control CompletedThis study tested whether adding cabergoline to letrozole helps women with PCOS ovulate better than letrozole alone. 100 women with PCOS took part. Researchers tracked ovulation using ultrasound. The goal was to find a more effective way to trigger ovulation in this common hormon…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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New Bladder-Saving combo offers hope against aggressive cancer
Disease control CompletedThis study tested a three-step treatment for people with muscle invasive bladder cancer: chemotherapy, then tumor removal through the urethra, then radiation. The goal was to save the bladder and improve quality of life compared to removing the bladder entirely. 97 patients took …
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Knee surgery showdown: which fix works best for meniscus root tears?
Disease control CompletedThis study compared two surgical techniques to repair a torn back part of the knee's cushion (medial meniscus root tear). Forty adults aged 20-50 with this tear were randomly assigned to one of two arthroscopic repair methods. The goal was to see which surgery better restores kne…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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Which surgery works best for kids with hirschsprung disease? new study compares two methods
Disease control CompletedThis study looked at 40 children with Hirschsprung disease who had one of two types of surgery to remove the diseased part of the colon and reconnect the healthy part to the anus. The goal was to see which technique led to better bowel function, like the ability to hold in stool …
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 02, 2026 11:58 UTC
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New study compares two surgical techniques for a common birth defect in boys
Disease control CompletedThis study looked at 80 children with a type of hypospadias (a birth defect where the urine opening is not at the tip of the penis) who had a narrow urethral plate. The researchers compared two different surgical repair methods to see which had fewer complications and better cosm…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 01, 2026 17:56 UTC
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New breathing device may offer alternative for COPD emergencies
Symptom relief CompletedThis study tested a new breathing support method (HVNI) against standard non-invasive ventilation (NIV) in 66 COPD patients with dangerously high carbon dioxide levels. The goal was to see if HVNI could safely lower carbon dioxide and reduce the need for a breathing tube. Results…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 22, 2026 12:09 UTC
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Thin jawbone? new study tests two ways to make room for implants
Symptom relief CompletedThis study tested two different tools (a special bur and a magnetic mallet) to widen a narrow jawbone so dental implants could be placed. Five adults with thin jawbones took part. The main goal was to see how stable the implant was right after placement. The study is complete, bu…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 22, 2026 12:08 UTC
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Could selenium soothe painful mouth sores?
Symptom relief CompletedThis study tested whether a selenium gel can help treat oral lichen planus, a chronic condition that causes painful sores in the mouth. Fifty adults with the condition used either selenium gel, a standard steroid cream, or an immunosuppressant cream. The goal was to see if seleni…
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 22, 2026 12:08 UTC
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New study finds best denture attachment for seniors
Symptom relief CompletedThis study tested two different attachment systems (Equator and Novaloc) for lower dentures held in place by dental implants. The goal was to see which one helps dentures stay in place better and improves quality of life for people with no teeth. 26 adults aged 60-70 took part. T…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 22, 2026 12:07 UTC
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Nose surgery may quiet snoring and ease sleep apnea
Symptom relief CompletedThis study looked at whether surgery to fix a blocked nose can improve snoring and sleep apnea in adults. Thirty people with nasal obstruction and sleep apnea had surgery. The main goal was to see if their breathing pauses during sleep (measured by the apnea-hypopnea index) got b…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 15, 2026 19:07 UTC
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Could skipping sedation help ventilated COPD patients recover faster?
Symptom relief CompletedThis study looked at 100 adults with COPD who needed a breathing tube and a ventilator. It compared two approaches: giving sedation with daily breaks versus giving no sedation at all. The goal was to see which method leads to more days off the ventilator and fewer complications i…
Phase: PHASE2 • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 08, 2026 13:13 UTC
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Egyptian study investigates Climate's role in Post-Surgery bleeding
Knowledge-focused CompletedThis completed study looked at 400 Egyptian adults who had open-heart surgery to see if living in a hot climate (Upper Egypt) versus a moderate climate (Lower Egypt) affected their bleeding after the operation. Researchers measured how much blood was lost in the first 24 hours an…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 24, 2026 02:34 UTC
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Timing matters: study reveals optimal gap between C-Sections
Knowledge-focused CompletedThis study looked at 201 women who had repeat C-sections to find the best time gap between surgeries. Researchers compared intervals from less than 12 months to over 48 months, tracking complications like bleeding, injuries, and blood transfusions. The goal is to help doctors and…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 24, 2026 02:33 UTC
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Ultrasound shows which breathing and fluids keep lungs open after surgery
Knowledge-focused CompletedThis study tested two methods to prevent lung collapse after upper abdominal surgery: one using a breathing machine setting (PEEP) and the other adding a lung-opening maneuver. Doctors used ultrasound to check how well the lungs stayed open in 60 adults. The goal was to see which…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:54 UTC
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Diabetes may impact dental pulp treatment success
Knowledge-focused CompletedThis study examined whether type 2 diabetes influences how well a dental procedure called pulpotomy works in adults. Researchers compared 70 diabetic and non-diabetic patients who had a molar treated for irreversible pulpitis. They checked the tooth's health, symptoms, and X-ray …
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:07 UTC
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Smoking slows gum healing: new study reveals protein clues
Knowledge-focused CompletedThis study looked at how smoking affects gum healing after non-surgical treatment for stage II gum disease. Researchers measured two proteins (PLAP-1 and Sclerostin) in the gum fluid of 36 smokers and non-smokers before and after deep cleaning. The goal was to understand if smoki…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:50 UTC
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Diabetes may worsen eye cell loss after cataract surgery, study finds
Knowledge-focused CompletedThis study looked at 100 people aged 40 and older who had cataract surgery. Half had type 2 diabetes and half did not. Researchers measured changes in the thin cell layer on the inside of the cornea before and after surgery to see if diabetes affects recovery. The goal is to help…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 17, 2026 12:10 UTC
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Bite force showdown: clear aligners vs. traditional braces in mild crowding
Knowledge-focused CompletedThis study looked at how clear aligners and fixed braces affect bite force after treating mild front tooth crowding. Twelve healthy people aged 14 to 22 with mild crowding and no extractions took part. The goal was to see which method leads to a better bite balance, using a T-sca…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 15, 2026 19:08 UTC
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Computer navigation in sinus surgery: a closer look at outcomes
Knowledge-focused CompletedThis study looked at whether using computer-assisted navigation during sinus surgery helps people with nasal polyps. Researchers compared surgery with and without this technology in 40 patients. They tracked how often polyps came back and how many complications occurred.
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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Dental bone graft showdown: which material works best for implants?
Knowledge-focused CompletedThis study tested two ways to rebuild jawbone for dental implants in 40 adults with narrow upper front jaws. One method used a block of bone from the chin mixed with cow-derived bone particles; the other used a synthetic material. Researchers measured bone width changes and compl…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 03, 2026 12:04 UTC